Sri Gene Detail

Summary

• Symbol
  Sri
• Name
  sorcin
• Synonyms
  2210417O06Rik, 2900070H08Rik, Sor

• Feature Type
  protein coding gene
• IDs
  MGI:98419
  NCBI Gene: 109552
• Gene Overview
  MyGene.info: SRI

Location & Maps

• Sequence Map
  Chr5:8046078-8069379 bp, + strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    23302 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 3.38 cM, cytoband A1
• Mapping Data
  5 experiments

Homology

• Human Ortholog
  SRI, sorcin

• Vertebrate Orthologs
  10

• Human Ortholog
  SRI, sorcin
  Orthology source: HomoloGene, HGNC
• Synonyms
  CP22, CP-22, SCN, V19
• Links
  HGNC:11292

  NCBI Gene ID: 6717

  neXtProt AC: NX_P30626

  UniProt: P30626

  
  
• Chr Location
  7q21.12; chr7:88205115-88226993 (-)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 37736
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: SRI
• Protein SuperFamily
  sorcin-like protein
• Gene Tree
  Sri
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  2
• Gene trapped
  1
• Targeted
  1
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  10 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  45
• GO References
  10

• External Resources
  FuncBase

Expression

• cDNA Data
  15

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase sri

Interactions

• Sri interacts with 259 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

Sequences &
Gene Models

• All Sequences
  53
• RefSeq
  8
• UniProt
  1
• CCDS
  CCDS19079.1, CCDS39009.1

• VEGA
  OTTMUSG00000025793 (Evidence)
• Ensembl
  ENSMUSG00000003161 (Evidence)
• NCBI Gene
  109552

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000025793	VEGA Gene Model | MGI Sequence Detail	23302	C57BL/6J
transcript	OTTMUST00000063524	VEGA | MGI Sequence Detail	2251	Not Applicable
polypeptide	OTTMUSP00000031410	VEGA | MGI Sequence Detail	198	Not Applicable

Polymorphisms

• SNPs within 2kb
  218 from dbSNP Build 142

• RFLP
  1

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000015619 sorcin
  (term hierarchy)
• InterPro Domains
  IPR018247 EF-Hand 1, calcium-binding site
  IPR002048 EF-hand domain
  IPR011992 EF-hand domain pair

Molecular
Reagents

• All nucleic 17

  cDNA 16

  Other 1

  
  

  Microarray probesets 7

Other
Accession IDs

MGD-MRK-14488, MGD-MRK-14598, MGI:1913777, MGI:1920275

References

• Summaries
  All 37

  Gene Ontology 10

  Phenotypes 4
• Earliest
  J:2349 Dernoncourt C, et al., Estimation of genetic distances between reeler and nearby loci on mouse chromosome 5. Genomics. 1991 Dec;11(4):1167-9
• Latest
  J:196242 Noordeen NA, et al., Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic beta-cells. Diabetes. 2012 Mar;61(3):574-85