About   Help   FAQ
Sox15
Gene Detail
 Symbol
Name
ID
Sox15
SRY (sex determining region Y)-box 15
MGI:98363
Feature Type protein coding gene
Genetic Map
Chromosome 11
42.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:69655314-69656727 bp, + strand
From VEGA annotation of GRCm38

  1414 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74586  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 dog

Gene Tree: Sox15

Human
homologs
Human Homolog SOX15, SRY (sex determining region Y)-box 15
NCBI Gene ID 6665
neXtProt AC  NX_O60248
Human Synonyms  SOX20, SOX26, SOX27
Human Chr (Location)  17p13.1; chr17:7588180-7590170 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(5) Targeted(3)
 
Mice homozygous for disruptions in this gene display abnormalities in muscle fiber differentiation and in muscle regeneration after injury.
 
Interactions
Sox15 interacts with 24 markers (Mir23b, Mir33, Mir122a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process cell differentiation, myoblast development, ...
Component cytoplasm, nuclear transcription factor complex, ...
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (159)    Tissues (92)    Images (21)
Theiler Stages: 2, 3, 4, 5, 15, 17, 19, 20, 21, 22, 23, 26, 28
Assay TypeResults
Immunohistochemistry 4
RNA in situ 40
RT-PCR 115
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) Genomic(2) cDNA(10) Primer pair(5)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000005991 (Evidence)
Ensembl Gene ModelENSMUSG00000041287 (Evidence)
Entrez Gene20670 (Evidence)
Consensus CDS ProjectCCDS24902.1
International Mouse Knockout Project StatusSox15
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005991 VEGA Gene Model | MGI Sequence Detail 1414 C57BL/6J ±  kb
transcript OTTMUST00000013405 VEGA | MGI Sequence Detail 861 Not Applicable 
polypeptide OTTMUSP00000006208 VEGA | MGI Sequence Detail 231 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(42 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009071 High mobility group (HMG) box domain
Protein Ontology PR:000015423 protein SOX-15
References (Earliest) J:4617 van de Wetering M, et al., Sox 15, a novel member of the murine Sox family of HMG box transcription factors. Nucleic Acids Res. 1993 Apr 11;21(7):1669
(Latest) J:197716 Ng CK, et al., Deciphering the Sox-Oct partner code by quantitative cooperativity measurements. Nucleic Acids Res. 2012 Jun;40(11):4933-41
All references(40)
Other
accession IDs
MGD-MRK-14502

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory