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Sox14 Gene Detail
Summary
  • Symbol
    Sox14
  • Name
    SRY (sex determining region Y)-box 14
  • Feature Type
    protein coding gene
  • IDs
    MGI:98362
    NCBI Gene: 20669
  • Gene Overview
    MyGene.info: SOX14
Location & Maps
more
  • Sequence Map
    Chr9:99874106-99876170 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2065 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 52.11 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SOX14, SRY-box 14
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SOX14, SRY-box 14
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SOX28
  • Links
    NCBI Gene ID: 8403
    neXtProt AC: NX_O95416

  • Chr Location
    3q22-q23; chr3:137764292-137766334 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 31224
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SOX14
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Sox14
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044377 VEGA Gene Model | MGI Sequence Detail 2065 C57BL/6J ±  kb
transcript OTTMUST00000116820 VEGA | MGI Sequence Detail 2065 Not Applicable  
polypeptide OTTMUSP00000065193 VEGA | MGI Sequence Detail 240 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    54 from dbSNP Build 142
  • PCR
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000015422 transcription factor SOX-14
  • InterPro Domains
    IPR009071 High mobility group box domain
    IPR022097 Transcription factor SOX
Molecular
Reagents
less
  • All nucleic 14
    Genomic 2
    cDNA 8
    Primer pair 2
    Other 2

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-14501
References
more
  • Summaries
    All 48
    Developmental Gene Expression 23
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:4011 Wright EM, et al., Seven new members of the Sox gene family expressed during mouse development. Nucleic Acids Res. 1993 Feb 11;21(3):744
  • Latest
    J:229536 Kawasaki K, et al., Expression of Sox genes in tooth development. Int J Dev Biol. 2015;59(10-12):471-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory