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Sox13
Gene Detail
 Symbol
Name
ID
Sox13
SRY (sex determining region Y)-box 13
MGI:98361
Feature Type protein coding gene
Genetic Map
Chromosome 1
57.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:133382303-133424377 bp, - strand
From VEGA annotation of GRCm38

  42075 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4159  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Sox13

Human
homologs
Human Homolog SOX13, SRY (sex determining region Y)-box 13
NCBI Gene ID 9580
neXtProt AC  NX_Q9UN79
Human Synonyms  ICA12, Sox-13
Human Chr (Location)  1q32; chr1:204073109-204127743 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(40) : Gene trapped(37) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele display impaired development of gamma-delta T cells and severe postnatal growth defects.
 
Interactions
Sox13 interacts with 214 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process regulation of gamma-delta T cell differentiation, regulation of transcription, DNA-templated, ...
Component nucleus
Function DNA binding, sequence-specific DNA binding
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (78)    Tissues (74)    Images (9)
Theiler Stages: 2, 3, 4, 5, 17, 18, 19, 20, 21, 22, 23, 26, 27, 28
Assay TypeResults
RNA in situ 60
Northern blot 6
RT-PCR 12
cDNA source data(61)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(64) cDNA(61) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026807 (Evidence)
Ensembl Gene ModelENSMUSG00000070643 (Evidence)
Entrez Gene20668 (Evidence)
UniGene8575
DFCITC1581842, TC1645166
DoTSDT.40177426, DT.97362239
NIA Mouse Gene IndexU021771
Consensus CDS ProjectCCDS48363.1
International Mouse Knockout Project StatusSox13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026807 VEGA Gene Model | MGI Sequence Detail 42075 C57BL/6J ±  kb
transcript OTTMUST00000066298 VEGA | MGI Sequence Detail 3693 Not Applicable 
polypeptide OTTMUSP00000033207 VEGA | MGI Sequence Detail 613 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(28) UniProt(2)
Polymorphisms SNPs within 2kb(559 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009071 High mobility group (HMG) box domain
Protein Ontology PR:000015421 transcription factor SOX-13
References (Earliest) J:4011 Wright EM, et al., Seven new members of the Sox gene family expressed during mouse development. Nucleic Acids Res. 1993 Feb 11;21(3):744
(Latest) J:197335 Gray EE, et al., Deficiency in IL-17-committed Vgamma4(+) gammadelta T cells in a spontaneous Sox13-mutant CD45.1(+) congenic mouse substrain provides protection from dermatitis. Nat Immunol. 2013 Jun;14(6):584-92
All references(53)
Other
accession IDs
MGD-MRK-14500, MGI:2138077, MGI:2138583, MGI:2138597

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory