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Sox13 Gene Detail
Summary
  • Symbol
    Sox13
  • Name
    SRY (sex determining region Y)-box 13
  • Feature Type
    protein coding gene
  • IDs
    MGI:98361
    NCBI Gene: 20668
  • Gene Overview
    MyGene.info: SOX13
Location & Maps
more
  • Sequence Map
    Chr1:133382303-133424377 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      42075 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 57.91 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SOX13, SRY-box 13
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SOX13, SRY-box 13
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ICA12, Sox-13
  • Links
    NCBI Gene ID: 9580
    neXtProt AC: NX_Q9UN79

  • Chr Location
    1q32.1; chr1:204073109-204127743 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4159
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SOX13
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 3 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    44
  • Chemically induced (other)
    2
  • Gene trapped
    37
  • Radiation induced
    1
  • Targeted
    3
  • Transgenic
    1
  • Genomic Mutations
    3 involving Sox13
  • Incidental Mutations
Mice homozygous for a knock-out allele display impaired development of gamma-delta T cells and severe postnatal growth defects.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026807 VEGA Gene Model | MGI Sequence Detail 42075 C57BL/6J ±  kb
transcript OTTMUST00000066298 VEGA | MGI Sequence Detail 3693 Not Applicable  
polypeptide OTTMUSP00000033207 VEGA | MGI Sequence Detail 613 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    557 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 61
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-14500, MGI:2138077, MGI:2138583, MGI:2138597
References
more
  • Summaries
    All 53
    Developmental Gene Expression 18
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:4011 Wright EM, et al., Seven new members of the Sox gene family expressed during mouse development. Nucleic Acids Res. 1993 Feb 11;21(3):744
  • Latest
    J:235366 Watanabe M, et al., Spatio-temporal expression of Sox genes in murine palatogenesis. Gene Expr Patterns. 2016 Jul;21(2):111-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory