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Son
Gene Detail
Symbol

Name
ID
Son
Son DNA binding protein
MGI:98353
Synonyms
2900011L12Rik, mKIAA1019
Feature Type
protein coding gene
Genetic Map
Chromosome 16
53.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:91647506-91679221 bp, + strand
From VEGA annotation of GRCm38

  31716 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10551  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 2 dog

HCOP human homology predictions: SON
Gene Tree: Son

Human
homologs
SON, SON DNA binding protein
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 6651
neXtProt AC: NX_P18583

Human Synonyms: BASS1, C21orf50, DBP-5, NREBP, SON3

Human Chr (Location): 21q22.11; chr21:33543038-33577514 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(43) : Gene trapped(36) Targeted(7)
Genomic Mutations involving Son (5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Son interacts with 442 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process cell cycle, cytokinesis, ...
Component nuclear speck, nucleoplasm, ...
Function DNA binding, nucleic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (340)    Tissues (161)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 309
Northern blot 13
RT-PCR 18
cDNA source data(27)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(33) Genomic(1) cDNA(29) Primer pair(2) Other(1)
Microarray probesets(11)
Other database
links
VEGA Gene Model OTTMUSG00000028340 (Evidence)
Ensembl Gene Model ENSMUSG00000022961 (Evidence)
Entrez Gene 20658 (Evidence)
Consensus CDS Project CCDS37399.1, CCDS37400.1
International Mouse Phenotyping Consortium Status Son
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028340 VEGA Gene Model | MGI Sequence Detail 31716 C57BL/6J ±  kb
transcript OTTMUST00000070236 VEGA | MGI Sequence Detail 8731 Not Applicable 
polypeptide OTTMUSP00000035760 VEGA | MGI Sequence Detail 2477 Not Applicable 

For the selected sequences
All sequences(129) RefSeq(22) UniProt(10)
Polymorphisms
SNPs within 2kb(94 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014720 Double-stranded RNA-binding-like domain
InterPro IPR000467 G-patch domain
InterPro IPR017986 WD40-repeat-containing domain
Protein Ontology PR:000015406 SON protein
References
(Earliest) J:12630 Cheng S, et al., GART, SON, IFNAR, and CRF2-4 genes cluster on human chromosome 21 and mouse chromosome 16. Mamm Genome. 1993;4(6):338-42
(Latest) J:197462 Dillman AA, et al., mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Nat Neurosci. 2013 Apr;16(4):499-506
All references(46)
Other
accession IDs
MGD-MRK-14487, MGI:1915461, MGI:2146338, MGI:2146586, MGI:2146715

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory