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Snrnp70 Gene Detail
Summary
  • Symbol
    Snrnp70
  • Name
    small nuclear ribonucleoprotein 70 (U1)
  • Synonyms
    2700022N21Rik, 3200002N22Rik, Rnulp70, Srnp70, U1-70
  • Feature Type
    protein coding gene
  • IDs
    MGI:98341
    NCBI Gene: 20637
  • Gene Overview
    MyGene.info: SNRNP70
Location & Maps
more
  • Sequence Map
    Chr7:45376462-45395692 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19231 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 29.28 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SNRNP70, small nuclear ribonucleoprotein U1 subunit 70
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SNRNP70, small nuclear ribonucleoprotein U1 subunit 70
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RNPU1Z, RPU1, Snp1, SNRP70, U170K, U1-70K, U1AP, U1RNP
  • Links
    NCBI Gene ID: 6625
    neXtProt AC: NX_P08621

  • Chr Location
    19q13.3; chr19:49085140-49108613 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    60
  • Gene trapped
    58
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063511 Ensembl Gene Model | MGI Sequence Detail 19231 C57BL/6J ±  kb
transcript ENSMUST00000074575 Ensembl | MGI Sequence Detail 1676 Not Applicable  
polypeptide ENSMUSP00000074160 Ensembl | MGI Sequence Detail 448 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    165 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000015338 U1 small nuclear ribonucleoprotein 70 kDa
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
    IPR022023 U1 small nuclear ribonucleoprotein of 70kDa N-terminal
Molecular
Reagents
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  • All nucleic 175
    Genomic 2
    cDNA 172
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-14003, MGD-MRK-14471, MGD-MRK-14602, MGI:1913569, MGI:1919842, MGI:2141914, MGI:2142381
References
more
  • Summaries
    All 48
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:23362 Query CC, et al., A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen. Cell. 1987 Oct 23;51(2):211-20
  • Latest
    J:204486 Zheng S, et al., A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing. Genome Res. 2013 Jun;23(6):998-1007

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory