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Sstr3
Gene Detail
 Symbol
Name
ID
Sstr3
somatostatin receptor 3
MGI:98329
Synonyms Smstr3, Smstr-3, sst3
Feature Type protein coding gene
Genetic Map
Chromosome 15
37.55 cM
Detailed Genetic Map ± 1 cM


Mapping data(14)
Sequence Map
Chr15:78537015-78544345 bp, - strand
From NCBI annotation of GRCm38

  7331 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20285  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: somatostatin receptor
Gene Tree: Sstr3

Human
homologs
Human Homolog SSTR3, somatostatin receptor 3
NCBI Gene ID 6753
neXtProt AC  NX_P32745
Human Synonyms  SS3R, SS-3-R, SS3-R, SSR-28
Human Chr (Location)  22q13.1; chr22:37204237-37220438 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Radiation induced(1) Targeted(3)
Genomic Mutations involving Sstr3 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sstr3 interacts with 191 markers (Mir10a, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process G-protein coupled receptor signaling pathway, signal transduction
Component ciliary membrane, cilium, ...
Function G-protein coupled receptor activity, signal transducer activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (47)    Tissues (46)    Images (1)
Theiler Stages: 21, 23, 28
Assay TypeResults
Immunohistochemistry 1
RT-PCR 46
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) Genomic(3) cDNA(5) Primer pair(5)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000044933 (Evidence)
Entrez Gene20607 (Evidence)
UniGene211411
DFCITC1585580
DoTSDT.91322480
NIA Mouse Gene IndexU036385
Consensus CDS ProjectCCDS27617.1
International Mouse Knockout Project StatusSstr3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 20607 NCBI Gene Model | MGI Sequence Detail 7331 C57BL/6J ±  kb
transcript NM_009218 RefSeq | MGI Sequence Detail 3928 Not Specified 
polypeptide P30935 UniProt | EBI | MGI Sequence Detail 428 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(6) UniProt(1)
Polymorphisms PCR(4) : SNPs within 2kb(121 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001856 Somatostatin receptor 3
InterPro IPR000586 Somatostatin receptor family
Protein Ontology PR:000001670 somatostatin receptor type 3
Graphical View of Protein Domain Structure
References (Earliest) J:2683 Yasuda K, et al., Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylylcyclase. J Biol Chem. 1992 Oct 5;267(28):20422-8
(Latest) J:194270 Guadiana SM, et al., Arborization of dendrites by developing neocortical neurons is dependent on primary cilia and type 3 adenylyl cyclase. J Neurosci. 2013 Feb 6;33(6):2626-38
All references(53)
Other
accession IDs
MGD-MRK-14456, MGD-MRK-14459

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory