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Sstr1
Gene Detail
Symbol

Name
ID
Sstr1
somatostatin receptor 1
MGI:98327
Synonyms
Smstr1, Smstr-1, sst1
Feature Type
protein coding gene
Genetic Map
Chromosome 12
25.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:58211772-58214444 bp, + strand
From VEGA annotation of GRCm38

  2673 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:820  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SSTR1
Protein SuperFamily: somatostatin receptor
Gene Tree: Sstr1

Human
homologs
SSTR1, somatostatin receptor 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6751
neXtProt AC: NX_P30872

Human Synonyms: SRIF-2, SS1R, SS-1-R, SS1-R

Human Chr (Location): 14q13; chr14:38207999-38213063 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display abnormal eye electrophysiology. Mice homozygous for a second targeted mutation display hypoactivity.
 
Interactions
Sstr1 interacts with 88 markers (Mir15a, Mir15b, Mir24-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (271)    Tissues (102)    Images (37)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 28
In situ reporter (knock in) 67
RT-PCR 176
cDNA source data(5)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase sstr1    NEW 
Molecular
reagents
All nucleic(13) Genomic(3) cDNA(5) Primer pair(4) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000037022 (Evidence)
Ensembl Gene Model ENSMUSG00000035431 (Evidence)
Entrez Gene 20605 (Evidence)
UniGene 278336
DFCI TC1589416
DoTS DT.91379145
NIA Mouse Gene Index U013980
Consensus CDS Project CCDS36456.1
International Mouse Phenotyping Consortium Status Sstr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037022 VEGA Gene Model | MGI Sequence Detail 2673 C57BL/6J ±  kb
transcript OTTMUST00000095213 VEGA | MGI Sequence Detail 1752 Not Applicable 
polypeptide OTTMUSP00000053112 VEGA | MGI Sequence Detail 391 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(4) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001116 Somatostatin receptor 1
InterPro IPR000586 Somatostatin receptor family
Protein Ontology PR:000001668 somatostatin receptor type 1
References
(Earliest) J:2346 Yamada Y, et al., Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):251-5
(Latest) J:190646 Bodmer D, et al., Somatostatin receptor types 1 and 2 in the developing Mammalian cochlea. Dev Neurosci. 2012;34(4):342-53
All references(55)
Other
accession IDs
MGD-MRK-14454, MGD-MRK-14457

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory