About   Help   FAQ
Sstr1
Gene Detail
 Symbol
Name
ID
Sstr1
somatostatin receptor 1
MGI:98327
Synonyms Smstr1, Smstr-1, sst1
Feature Type protein coding gene
Genetic Map
Chromosome 12
25.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:58211772-58213887 bp, + strand
From VEGA annotation of GRCm38

  2116 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:820  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: somatostatin receptor
Gene Tree: Sstr1

Human
homologs
Human Homolog SSTR1, somatostatin receptor 1
NCBI Gene ID 6751
neXtProt AC  NX_P30872
Human Synonyms  SRIF-2, SS1R, SS-1-R, SS1-R
Human Chr (Location)  14q13; chr14:38207999-38213063 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display abnormal eye electrophysiology. Mice homozygous for a second targeted mutation display hypoactivity.
 
Interactions
Sstr1 interacts with 88 markers (Mir15a, Mir15b, Mir24-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process glutamate receptor signaling pathway, G-protein coupled receptor signaling pathway, ...
Component cytoplasm, integral component of membrane, ...
Function G-protein coupled receptor activity, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (271)    Tissues (102)    Images (37)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 28
In situ reporter (knock in) 67
RT-PCR 176
cDNA source data(5)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) Genomic(3) cDNA(5) Primer pair(4) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037022 (Evidence)
Ensembl Gene ModelENSMUSG00000035431 (Evidence)
Entrez Gene20605 (Evidence)
UniGene278336
DFCITC1589416
DoTSDT.91379145
NIA Mouse Gene IndexU013980
Consensus CDS ProjectCCDS36456.1
International Mouse Knockout Project StatusSstr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037022 VEGA Gene Model | MGI Sequence Detail 2116 C57BL/6J ±  kb
transcript OTTMUST00000095213 VEGA | MGI Sequence Detail 1752 Not Applicable 
polypeptide OTTMUSP00000053112 VEGA | MGI Sequence Detail 391 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(4) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001116 Somatostatin receptor 1
InterPro IPR000586 Somatostatin receptor family
Protein Ontology PR:000001668 somatostatin receptor type 1
References (Earliest) J:2346 Yamada Y, et al., Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):251-5
(Latest) J:190646 Bodmer D, et al., Somatostatin receptor types 1 and 2 in the developing Mammalian cochlea. Dev Neurosci. 2012;34(4):342-53
All references(56)
Other
accession IDs
MGD-MRK-14454, MGD-MRK-14457

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory