Shbg
Gene Detail

Symbol Name ID

Shbg sex hormone binding globulin MGI:98295

Feature Type

protein coding gene

Genetic Map

Chromosome 11

42.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(17)

Sequence Map

Chr11:69614804-69617905 bp, - strand From VEGA annotation of GRCm38   3102 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:813  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: sex steroid-binding protein
Gene Tree: Shbg

Human homologs

Human Homolog		SHBG, sex hormone-binding globulin
NCBI Gene ID		6462
neXtProt AC		NX_P04278
Human Synonyms		ABP, SBP, TEBG
Human Chr (Location)		17p13.1; chr17:7614064-7633383 (+)  GRCh38

Mutations, alleles, and phenotypes

All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Shbg interacts with 31 markers (Mir9-1, Mir9-2, Mir9-3, ...)

View All

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	primary spermatocyte growth
Component	extracellular region, extracellular vesicular exosome
Function	lipid binding, steroid binding

External Resources: FuncBase

Expression

Literature Summary: (1 records)

Data Summary: Results (3)    Tissues (1)   
Theiler Stages: 28

Assay Type	Results
RT-PCR	3

cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular reagents

All nucleic(7) cDNA(4) Primer pair(2) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000005986 (Evidence)
Ensembl Gene Model	ENSMUSG00000005202 (Evidence)
Entrez Gene	20415 (Evidence)
UniGene	1431
DFCI	TC1593084
DoTS	DT.55223080
NIA Mouse Gene Index	U032971
Consensus CDS Project	CCDS24899.1
International Mouse Knockout Project Status	Shbg

Sequences

Length	Strain/Species
genomic	OTTMUSG00000005986	VEGA Gene Model | MGI Sequence Detail	3102	C57BL/6J
transcript	OTTMUST00000013396	VEGA | MGI Sequence Detail	1419	Not Applicable
polypeptide	OTTMUSP00000006202	VEGA | MGI Sequence Detail	403	Not Applicable

All sequences(19) RefSeq(2) UniProt(1)

Polymorphisms

All PCR and RFLP(5) : PCR(1) RFLP(4) SNPs within 2kb(38 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR008985	Concanavalin A-like lectin/glucanases superfamily
InterPro	IPR013320	Concanavalin A-like lectin/glucanase, subgroup
InterPro	IPR001791	Laminin G domain
Protein Ontology	PR:000014836	sex hormone-binding globulin

References

(Earliest) J:14613 Dlouhy SR, et al., Production of an antibody to mouse salivary androgen binding protein (ABP) and its use in identifying a prostate protein produced by a gene distinct from Abp. Biochem Genet. 1986 Oct;24(9-10):743-63
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(45)

Other accession IDs

MGD-MRK-14401