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Shbg Gene Detail
Summary
  • Symbol
    Shbg
  • Name
    sex hormone binding globulin
  • Feature Type
    protein coding gene
  • IDs
    MGI:98295
    NCBI Gene: 20415
  • Gene Overview
    MyGene.info: SHBG
Location & Maps
more
  • Sequence Map
    Chr11:69614804-69617905 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      3102 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.86 cM
  • Mapping Data
    17 experiments
Homology
more
  • Human Ortholog
    SHBG, sex hormone binding globulin
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SHBG, sex hormone binding globulin
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ABP, SBP, TEBG
  • Links
    NCBI Gene ID: 6462
    neXtProt AC: NX_P04278

  • Chr Location
    17p13.1; chr17:7614064-7633383 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Shbg
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    3
  • Tissues
    1
  • cDNA Data
    4
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005986 VEGA Gene Model | MGI Sequence Detail 3102 C57BL/6J ±  kb
transcript OTTMUST00000013396 VEGA | MGI Sequence Detail 1419 Not Applicable  
polypeptide OTTMUSP00000006202 VEGA | MGI Sequence Detail 403 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    37 from dbSNP Build 142
  • PCR
    1
  • RFLP
    4
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014836 sex hormone-binding globulin
  • InterPro Domains
    IPR013320 Concanavalin A-like lectin/glucanase domain
    IPR001791 Laminin G domain
Molecular
Reagents
less
  • All nucleic 7
    cDNA 4
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14401
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 14
  • Earliest
    J:14613 Dlouhy SR, et al., Production of an antibody to mouse salivary androgen binding protein (ABP) and its use in identifying a prostate protein produced by a gene distinct from Abp. Biochem Genet. 1986 Oct;24(9-10):743-63
  • Latest
    J:220734 Zhang L, et al., Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4003-8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory