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Srsf5 Gene Detail
Summary
  • Symbol
    Srsf5
  • Name
    serine/arginine-rich splicing factor 5
  • Synonyms
    Sfrs5
  • Feature Type
    protein coding gene
  • IDs
    MGI:98287
    NCBI Gene: 20384
  • Gene Overview
    MyGene.info: SRSF5
Location & Maps
more
  • Sequence Map
    Chr12:80945520-80950503 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      4984 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 37.20 cM, cytoband D2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SRSF5, serine and arginine rich splicing factor 5
  • Vertebrate Orthologs
    3
  • Human Ortholog
    SRSF5, serine and arginine rich splicing factor 5
    Orthology source: HGNC
  • Synonyms
    HRS, SFRS5, SRP40
  • Links
    NCBI Gene ID: 6430
    neXtProt AC: NX_Q13243

  • Chr Location
    14q24; chr14:69767095-69772005 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Gene trapped
    13
  • Targeted
    1
  • Genomic Mutations
    1 involving Srsf5
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    28
  • Tissues
    28
  • cDNA Data
    486
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021161 VEGA Gene Model | MGI Sequence Detail 4984 C57BL/6J ±  kb
transcript OTTMUST00000050131 VEGA | MGI Sequence Detail 1489 Not Applicable  
polypeptide OTTMUSP00000023360 VEGA | MGI Sequence Detail 270 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    6 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000014762 serine/arginine-rich splicing factor 5
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
Molecular
Reagents
less
  • All nucleic 492
    Genomic 5
    cDNA 486
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14375
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:45103 Du K, et al., Alternative splicing and structure of the human and mouse SFRS5/HRS/SRp40 genes. Gene. 1997 Dec 19;204(1-2):243-9
  • Latest
    J:160815 Manley JL, et al., A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). Genes Dev. 2010 Jun 1;24(11):1073-4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory