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Sar1a Gene Detail
Summary
  • Symbol
    Sar1a
  • Name
    secretion associated Ras related GTPase 1A
  • Synonyms
    1600019H17Rik, Sara1
  • Feature Type
    protein coding gene
  • IDs
    MGI:98230
    NCBI Gene: 20224
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr10:61680304-61693297 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12994 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 32.26 cM, cytoband B4
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SAR1A, secretion associated Ras related GTPase 1A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SAR1A, secretion associated Ras related GTPase 1A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    masra2, SAR1, Sara, SARA1
  • Links
    NCBI Gene ID: 56681
    neXtProt AC: NX_Q9NR31
    UniProt: Q9NR31

  • Chr Location
    10q22.1; chr10:70150204-70170529 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20224 NCBI Gene Model | MGI Sequence Detail 12994 C57BL/6J ±  kb
transcript NM_001358487 RefSeq | MGI Sequence Detail 2780 C57BL/6  
polypeptide P36536 UniProt | EBI | MGI Sequence Detail 198 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    69 from dbSNP Build 142
Protein
Information
less
  • UniProt
    7 Sequences
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR006689 Small GTPase superfamily, ARF/SAR type
    IPR006687 Small GTPase superfamily, SAR1-type
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-14289, MGI:1915163
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:221071 Chang HM, et al., The FYVE domain of Smad Anchor for Receptor Activation (SARA) is required to prevent skin carcinogenesis, but not in mouse development. PLoS One. 2014;9(8):e105299

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/13/2017
MGI 6.11
The Jackson Laboratory