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Saa3
Gene Detail
Symbol

Name
ID
Member of
Saa3
serum amyloid A 3
MGI:98223
Saa cluster
STS
Synonyms
l7R3, Saa-3
Feature Type
protein coding gene
Genetic Map
Chromosome 7
30.51 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr7:46711998-46715676 bp, - strand
From NCBI annotation of GRCm38

  3679 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:137239  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

HCOP human homology predictions: SAA3P
Protein SuperFamily: amyloid protein, SAA type
Gene Tree: Saa3

Human
homologs
SAA3P, serum amyloid A3 pseudogene
Orthology source: HGNC

IDs:
NCBI Gene ID: 6290

Human Synonyms: SAA3

Human Chr (Location): 11p15.1; chr11:18112472-18116132 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Chemically induced (ENU)(2) Gene trapped(3) Targeted(5)
 
Two chemically induced mutations result in prenatal lethality in homozygous mice.
 
Interactions
Saa3 interacts with 8 markers (Mir30b, Mir205, Mir337, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process acute-phase response, cell chemotaxis, ...
Component extracellular region, extracellular space, ...
Function chemoattractant activity, Toll-like receptor 4 binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (2)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 2
cDNA source data(13)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(28) Genomic(12) cDNA(14) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000040026 (Evidence)
Entrez Gene 20210 (Evidence)
UniGene 14277
DFCI TC1579237, TC1657634
DoTS DT.487830, DT.99856495
NIA Mouse Gene Index U028559
PDB 4Q5G
Consensus CDS Project CCDS21282.1
International Mouse Phenotyping Consortium Status Saa3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 20210 NCBI Gene Model | MGI Sequence Detail 3679 C57BL/6J ±  kb
transcript NM_011315 RefSeq | MGI Sequence Detail 531 C57BL/6 
polypeptide P04918 UniProt | EBI | MGI Sequence Detail 122 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000096 Serum amyloid A protein
Protein Ontology PR:000015919 murine-type serum amyloid A-3 protein
Graphical View of Protein Domain Structure
References
(Earliest) J:30484 Taylor BA, et al., Detailed mapping of serum amyloid A complex (Saa) on Chr 7. Mouse News Lett. 1984;71:31
(Latest) J:204247 Kasahara DI, et al., Role of the adiponectin binding protein, T-cadherin (cdh13), in pulmonary responses to subacute ozone. PLoS One. 2013;8(6):e65829
All references(54)
Other
accession IDs
MGD-MRK-14275, MGD-MRK-14280, MGI:1890512, MGI:2142177

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory