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Rps4x
Gene Detail
 Symbol
Name
ID
Rps4x
ribosomal protein S4, X-linked
MGI:98158
Synonyms Rps4, Rps4-1
Feature Type protein coding gene
Genetic Map
Chromosome X
45.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
ChrX:102184941-102189394 bp, - strand
From VEGA annotation of GRCm38

  4454 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133576  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Protein SuperFamily: ribosomal protein S4a/S4e
Gene Tree: Rps4x

Human
homologs
Human Homolog RPS4Y1, ribosomal protein S4, Y-linked 1
NCBI Gene ID 6192
neXtProt AC  NX_P22090
Human Synonyms  RPS4Y, S4
Human Chr (Location)  Yp11.3; chrY:2841582-2866956 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(7)
 
Rps4x, Ube1x, and Zfx are subject to X-inactivation in mouse but not in human, suggesting that Turner syncrome may be in part due to insufficiency in these gene products.
 
Interactions
Rps4x interacts with 18 markers (Mir24-1, Mir24-2, Mir101a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process multicellular organismal development, translation
Component cytoplasm, intracellular, ...
Function RNA binding, rRNA binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (48)    Tissues (47)    Images (2)
Theiler Stages: 17, 21, 23, 28
Assay TypeResults
RT-PCR 48
cDNA source data(865)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(870) Genomic(2) cDNA(866) Primer pair(2)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000018303 (Evidence)
Ensembl Gene ModelENSMUSG00000031320 (Evidence)
Entrez Gene20102 (Evidence)
UniGene66
DFCITC1573686, TC1596623
DoTSDT.102559214, DT.91358103, DT.94210107, DT.94210202, DT.94210222
NIA Mouse Gene IndexU022801, U039586, U045275, U053308, U130574, U131085
Consensus CDS ProjectCCDS41083.1
International Mouse Knockout Project StatusRps4x
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018303 VEGA Gene Model | MGI Sequence Detail 4454 C57BL/6J ±  kb
transcript OTTMUST00000044225 VEGA | MGI Sequence Detail 975 Not Applicable 
polypeptide OTTMUSP00000019879 VEGA | MGI Sequence Detail 263 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(2) UniProt(4)
Polymorphisms RFLP(2) : SNPs within 2kb(1 from dbSNP Build 137)    SNPs within 2kb including multiple locations(3)
Protein-related
information
ResourceIDDescription
InterPro IPR005824 KOW
InterPro IPR000876 Ribosomal protein S4e
InterPro IPR013845 Ribosomal protein S4e, central region
InterPro IPR013843 Ribosomal protein S4e, N-terminal
InterPro IPR018199 Ribosomal protein S4e, N-terminal, conserved site
InterPro IPR002942 RNA-binding S4 domain
Protein Ontology PR:000014277 40S ribosomal protein S4, X isoform
References (Earliest) J:10892 Fisher EM, et al., Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. Cell. 1990 Dec 21;63(6):1205-18
(Latest) J:173414 Kondrashov N, et al., Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Cell. 2011 Apr 29;145(3):383-97
All references(47)
Other
accession IDs
MGD-MRK-14174, MGD-MRK-14185

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory