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Rps4x Gene Detail
Summary
  • Symbol
    Rps4x
  • Name
    ribosomal protein S4, X-linked
  • Synonyms
    Rps4, Rps4-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:98158
    NCBI Gene: 20102
Location & Maps
more
  • Sequence Map
    ChrX:102184941-102189394 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4454 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    RPS4X, ribosomal protein S4, X-linked
  • Vertebrate Orthologs
    7
  • Human Ortholog
    RPS4X, ribosomal protein S4, X-linked
    Orthology source: HGNC
  • Synonyms
    CCG2, DXS306, RPS4, S4, SCAR, SCR10
  • Links
    NCBI Gene ID: 6191
    neXtProt AC: NX_P62701

  • Chr Location
    Xq13.1; chrX:72272603-72277291 (-)  GRCh38.p2

  • Human Ortholog
    RPS4Y1, ribosomal protein S4, Y-linked 1
    Orthology source: HomoloGene
  • Synonyms
    RPS4Y, S4
  • Links
    NCBI Gene ID: 6192
    neXtProt AC: NX_P22090

  • Chr Location
    Yp11.3; chrY:2841582-2866956 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    7
Rps4x, Ube1x, and Zfx are subject to X-inactivation in mouse but not in human, suggesting that Turner syncrome may be in part due to insufficiency in these gene products.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018303 VEGA Gene Model | MGI Sequence Detail 4454 C57BL/6J ±  kb
transcript OTTMUST00000044225 VEGA | MGI Sequence Detail 975 Not Applicable  
polypeptide OTTMUSP00000019879 VEGA | MGI Sequence Detail 263 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1 from dbSNP Build 137
  • RFLP
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000014277 40S ribosomal protein S4, X isoform
  • InterPro Domains
    IPR032277 40S ribosomal protein S4, C-terminal domain
    IPR000876 Ribosomal protein S4e
    IPR013845 Ribosomal protein S4e, central region
    IPR013843 Ribosomal protein S4e, N-terminal
    IPR018199 Ribosomal protein S4e, N-terminal, conserved site
    IPR002942 RNA-binding S4 domain
Molecular
Reagents
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  • All nucleic 870
    Genomic 2
    cDNA 866
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
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MGD-MRK-14174, MGD-MRK-14185
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:10892 Fisher EM, et al., Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. Cell. 1990 Dec 21;63(6):1205-18
  • Latest
    J:173414 Kondrashov N, et al., Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Cell. 2011 Apr 29;145(3):383-97

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory