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Rps4x Gene Detail
Summary
  • Symbol
    Rps4x
  • Name
    ribosomal protein S4, X-linked
  • Synonyms
    Rps4, Rps4-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:98158
    NCBI Gene: 20102
  • Gene Overview
    MyGene.info: RPS4X
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:102184941-102189391 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 45.20 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98158
protein coding gene ChrX:102184941-102189394 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035971
protein coding gene ChrX:98767914-98772367 (-)
A/J MGP_AJ_G0035956
protein coding gene ChrX:98721257-98726163 (-)
AKR/J MGP_AKRJ_G0035872
protein coding gene ChrX:101579883-101588039 (-)
BALB/cJ MGP_BALBcJ_G0035941
protein coding gene ChrX:97462551-97467133 (-)
C3H/HeJ MGP_C3HHeJ_G0035649
protein coding gene ChrX:99146347-99150800 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036469
protein coding gene ChrX:101697444-101701897 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033298
protein coding gene ChrX:96433178-96437747 (-)
CAST/EiJ MGP_CASTEiJ_G0034935
protein coding gene ChrX:83462201-83466661 (-)
CBA/J MGP_CBAJ_G0035623
protein coding gene ChrX:104848629-104853075 (-)
DBA/2J MGP_DBA2J_G0035777
protein coding gene ChrX:97944086-97948540 (-)
FVB/NJ MGP_FVBNJ_G0035716
protein coding gene ChrX:97305898-97310679 (-)
LP/J MGP_LPJ_G0035868
protein coding gene ChrX:99685944-99692783 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035750
protein coding gene ChrX:109368830-109375490 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036495
protein coding gene ChrX:98419628-98424075 (-)
PWK/PhJ MGP_PWKPhJ_G0034634
protein coding gene ChrX:81031004-81035561 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034462
protein coding gene ChrX:84368881-84373673 (-)
WSB/EiJ MGP_WSBEiJ_G0035074
protein coding gene ChrX:97124647-97129723 (-)



Homology
more
  • Human Ortholog
    RPS4X, ribosomal protein S4 X-linked
  • Vertebrate Orthologs
    7
  • Human Ortholog
    RPS4X, ribosomal protein S4 X-linked
    Orthology source: HGNC
  • Synonyms
    CCG2, DXS306, RPS4, S4, SCAR, SCR10
  • Links
    NCBI Gene ID: 6191
    neXtProt AC: NX_P62701
    UniProt: P62701

  • Chr Location
    Xq13.1; chrX:72272603-72277291 (-)  GRCh38.p7

  • Human Ortholog
    RPS4Y1, ribosomal protein S4 Y-linked 1
    Orthology source: HomoloGene
  • Synonyms
    RPS4Y, S4
  • Links
    NCBI Gene ID: 6192
    neXtProt AC: NX_P22090
    UniProt: P22090

  • Chr Location
    Yp11.2; chrY:2841582-2866956 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Rps4x, Ube1x, and Zfx are subject to X-inactivation in mouse but not in human, suggesting that Turner syncrome may be in part due to insufficiency in these gene products.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20102 NCBI Gene Model | MGI Sequence Detail 4451 C57BL/6J ±  kb
transcript NM_009094 RefSeq | MGI Sequence Detail 992 C57BL/6  
polypeptide P62702 UniProt | EBI | MGI Sequence Detail 263 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 870
    Genomic 2
    cDNA 866
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-14174, MGD-MRK-14185
References
more
  • Summaries
    All 46
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 2
  • Earliest
    J:10892 Fisher EM, et al., Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. Cell. 1990 Dec 21;63(6):1205-18
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory