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Rps14 Gene Detail
Summary
  • Symbol
    Rps14
  • Name
    ribosomal protein S14
  • Synonyms
    2600014J02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:98107
    NCBI Gene: 20044
  • Gene Overview
    MyGene.info: RPS14
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:60774596-60778546 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 34.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98107
protein coding gene Chr18:60774510-60778546 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024467
protein coding gene Chr18:60604588-60608624 (+)
A/J MGP_AJ_G0024434
protein coding gene Chr18:58008139-58012264 (+)
AKR/J MGP_AKRJ_G0024404
protein coding gene Chr18:59605276-59609314 (+)
BALB/cJ MGP_BALBcJ_G0024433
protein coding gene Chr18:58137286-58141435 (+)
C3H/HeJ MGP_C3HHeJ_G0024201
protein coding gene Chr18:59840782-59844818 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024880
protein coding gene Chr18:62257222-62261258 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022311
protein coding gene Chr18:57559131-57563229 (+)
CAST/EiJ MGP_CASTEiJ_G0023674
protein coding gene Chr18:59705601-59710583 (+)
CBA/J MGP_CBAJ_G0024171
protein coding gene Chr18:64274541-64278686 (+)
DBA/2J MGP_DBA2J_G0024301
protein coding gene Chr18:57687749-57691785 (+)
FVB/NJ MGP_FVBNJ_G0024267
protein coding gene Chr18:57093730-57097771 (+)
LP/J MGP_LPJ_G0024384
protein coding gene Chr18:60461569-60465605 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024296
protein coding gene Chr18:65910968-65915021 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024927
protein coding gene Chr18:59805168-59809204 (+)
PWK/PhJ MGP_PWKPhJ_G0023417
protein coding gene Chr18:57912315-57916459 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023223
protein coding gene Chr18:60042767-60046922 (+)
WSB/EiJ MGP_WSBEiJ_G0023738
protein coding gene Chr18:59656761-59660797 (+)



Homology
more
  • Human Ortholog
    RPS14, ribosomal protein S14
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RPS14, ribosomal protein S14
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EMTB, S14
  • Links
    NCBI Gene ID: 6208
    neXtProt AC: NX_P62263
    UniProt: P62263

  • Chr Location
    5q33.1; chr5:150444229-150449810 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human RPS14 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Conditional heterozygous knockout in hematopoietic cells leads to reduced protein synthesis, resulting in progressive anemia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20044 NCBI Gene Model | MGI Sequence Detail 3951 C57BL/6J ±  kb
transcript NM_020600 RefSeq | MGI Sequence Detail 606 C57BL/6  
polypeptide P62264 UniProt | EBI | MGI Sequence Detail 151 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 674
    cDNA 674

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-14133, MGI:1914326, MGI:2139854
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:1700 Johnson KR, et al., A multipoint genetic linkage map of mouse chromosome 18. Genomics. 1992 Aug;13(4):1143-9
  • Latest
    J:267091 Fink EC, et al., Crbn (I391V) is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice. Blood. 2018 Oct 4;132(14):1535-1544

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory