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Rpn2
Gene Detail
Symbol

Name
ID
Rpn2
ribophorin II
MGI:98085
Synonyms
1300012C06Rik, Rpn-2
Feature Type
protein coding gene
Genetic Map
Chromosome 2
78.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr2:157279017-157326319 bp, + strand
From VEGA annotation of GRCm38

  47303 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2214  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: oligosaccharyltransferase, ribophorin II (Swp1p) subunit
Gene Tree: Rpn2

Human
homologs
Human Homolog RPN2, ribophorin II
NCBI Gene ID 6185
neXtProt AC  NX_P04844
Human Synonyms  RIBIIR, RPNII, RPN-II, SWP1
Human Chr (Location)  20q12-q13.1; chr20:37179051-37241623 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(18) : Gene trapped(16) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rpn2 interacts with 153 markers (Mir7-2, Mir7b, Mir17, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process protein N-linked glycosylation
Component autophagic vacuole membrane, endoplasmic reticulum, ...
Function ribosome binding, transferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (95)    Tissues (95)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 95
cDNA source data(500)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(502) cDNA(501) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000016167 (Evidence)
Ensembl Gene ModelENSMUSG00000027642 (Evidence)
Entrez Gene20014 (Evidence)
UniGene22130
DFCITC1573840, TC1595184, TC1740157, TC1758634
DoTSDT.101311777, DT.101720512, DT.103577938, DT.111093367, DT.55107448, DT.97335371, DT.97372648
NIA Mouse Gene IndexU002737
EC2.4.99.18
Consensus CDS ProjectCCDS16975.1
International Mouse Knockout Project StatusRpn2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016167 VEGA Gene Model | MGI Sequence Detail 47303 C57BL/6J ±  kb
transcript OTTMUST00000038674 VEGA | MGI Sequence Detail 2756 Not Applicable 
polypeptide OTTMUSP00000017300 VEGA | MGI Sequence Detail 631 Not Applicable 

For the selected sequences
All sequences(83) RefSeq(10) UniProt(7)
Polymorphisms
RFLP(1) : SNPs within 2kb(509 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008814 Ribophorin II
Protein Ontology PR:000014241 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
References
(Earliest) J:4880 Barton DE, et al., The genes for ribophorins I and II are on human Chromosomes 3q and 20 and mouse Chromosomes 6 and 2, respectively. Cytogenet Cell Genet. 1987;46:577
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(46)
Other
accession IDs
MGD-MRK-14108, MGD-MRK-14110, MGI:1914153, MGI:2139263

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory