Rpl7 MGI Mouse Gene Detail - MGI:98073

Symbol

Rpl7
Name

ribosomal protein L7
Synonyms

Rpl7a, Surf-3

Feature Type

protein coding gene
IDs

MGI:98073
NCBI Gene: 19989
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr1:16171519-16174657 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 4.94 cM, cytoband A3
Mapping Data

2 experiments

SNPs within 2kb

11 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_98073	protein coding gene	Chr1:16171519-16174886 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0015853	protein coding gene	Chr1:13575738-13580761 (-)
A/J	MGP_AJ_G0015834	protein coding gene	Chr1:13424902-13428264 (-)
AKR/J	MGP_AKRJ_G0015793	protein coding gene	Chr1:13446420-13449727 (-)
BALB/cJ	MGP_BALBcJ_G0015790	protein coding gene	Chr1:13149314-13152671 (-)
C3H/HeJ	MGP_C3HHeJ_G0015624	protein coding gene	Chr1:13450960-13454221 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0016244	protein coding gene	Chr1:14190968-14196285 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0013965	protein coding gene	Chr1:12043257-12046408 (-)
CAST/EiJ	MGP_CASTEiJ_G0015205	protein coding gene	Chr1:13538001-13541332 (-)
CBA/J	MGP_CBAJ_G0015597	protein coding gene	Chr1:14499246-14504617 (-)
DBA/2J	MGP_DBA2J_G0015696	protein coding gene	Chr1:13015584-13018981 (-)
FVB/NJ	MGP_FVBNJ_G0015701	protein coding gene	Chr1:12836252-12839618 (-)
LP/J	MGP_LPJ_G0015768	protein coding gene	Chr1:13782394-13787652 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0015720	protein coding gene	Chr1:15156037-15159964 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016291	protein coding gene	Chr1:13403552-13406359 (-)
PWK/PhJ	MGP_PWKPhJ_G0014989	protein coding gene	Chr1:12821329-12824746 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0014770	protein coding gene	Chr1:13586572-13591595 (-)
WSB/EiJ	MGP_WSBEiJ_G0015268	protein coding gene	Chr1:13338843-13341975 (-)

Human Ortholog

RPL7, ribosomal protein L7

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPL7, ribosomal protein L7
Synonyms

humL7-1, L7, uL30
Links

HGNC:10363

NCBI Gene ID: 6129

neXtProt AC: NX_P18124

UniProt: P18124
Chr Location

8q21.11; chr8:73290242-73295789 (-) GRCh38

MGI Vertebrate Homology

Rpl7 stringent orthology
1 human;1 mouse;2 rat;1 zebrafish
HCOP

vertebrate homology predictions: RPL7
Gene Tree

Rpl7

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

7
Gene trapped

6
Targeted

1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

19 strains or lines available

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All GO Annotations

33
GO References

10

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

727
Tissues

13
cDNA Data

24
Literature Summary

15

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rpl7

ZFIN rpl7

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All Sequences

63
RefSeq

2
UniProt

5
CCDS

CCDS14829.1

Ensembl

ENSMUSG00000043716 (Evidence)
NCBI Gene

19989

			Length	Strain/Species	Flank
genomic	19989	NCBI Gene Model \| MGI Sequence Detail	3139	C57BL/6J	± kb
transcript	NM_011291	RefSeq \| MGI Sequence Detail	937	C57BL/6
polypeptide	P14148	UniProt \| EBI \| MGI Sequence Detail	270	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000014232 eukaryotic-type large ribosomal subunit protein uL30

(term hierarchy)
PDB

6SWA, 7CPU, 7CPV, 7LS1, 7LS2
InterPro Domains

IPR039699 Large ribosomal subunit protein uL30

IPR018038 Large ribosomal subunit protein uL30, conserved site

IPR005998 Large ribosomal subunit protein uL30, eukaryotic

IPR035808 Large ribosomal subunit protein uL30, eukaryotic/archaeal

IPR036919 Large ribosomal subunit protein uL30, ferredoxin-like fold domain superfamily

IPR016082 Large ribosomal subunit protein uL30-like, ferredoxin-like fold domain

IPR012988 Large ribosomal subunit protein uL30, N-terminal, eukaryotes

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All nucleic 29

cDNA 25

Primer pair 4

Microarray probesets 9

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MGD-MRK-14096, MGD-MRK-14646

Summaries

All 58

Developmental Gene Expression 15

Gene Ontology 10

Phenotypes 4
Earliest

J:31514 Meyuhas O, et al., Construction and identification of cDNA clones for mouse ribosomal proteins: application for the study of r-protein gene expression. Gene. 1980 Jul;10(2):113-29
Latest

J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

TSS for Rpl7:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr11035	Chr1:16174620-16174659 (-)	17 bp
Tssr11034	Chr1:16174609-16174616 (-)	44 bp
Tssr11033	Chr1:16174387-16174428 (-)	249 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23