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Rmrp Gene Detail
Summary
  • Symbol
    Rmrp
  • Name
    RNA component of mitochondrial RNAase P
  • Synonyms
    Rmrpr, RNase MRP
Location &
Maps
more
  • Sequence Map
    Chr4:43492785-43493059 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 23.04 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97937
RNase MRP RNA gene Chr4:43492783-43493063 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036798
ribozyme gene Chr4:41610494-41610764 (-)
A/J MGP_AJ_G0036784
ribozyme gene Chr4:40134681-40134951 (-)
AKR/J MGP_AKRJ_G0036733
ribozyme gene Chr4:41047025-41047295 (-)
BALB/cJ MGP_BALBcJ_G0036774
ribozyme gene Chr4:40222152-40222422 (-)
C3H/HeJ MGP_C3HHeJ_G0036463
ribozyme gene Chr4:41672357-41672627 (-)
C57BL/6NJ MGP_C57BL6NJ_G0037289
ribozyme gene Chr4:43171939-43172209 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0034356
ribozyme gene Chr4:37581612-37581882 (-)
CAST/EiJ MGP_CASTEiJ_G0035653
ribozyme gene Chr4:41176141-41176411 (-)
CBA/J MGP_CBAJ_G0036438
ribozyme gene Chr4:44475643-44475913 (-)
DBA/2J MGP_DBA2J_G0036612
ribozyme gene Chr4:40043176-40043446 (-)
FVB/NJ MGP_FVBNJ_G0036566
ribozyme gene Chr4:39264538-39264808 (-)
LP/J MGP_LPJ_G0036659
ribozyme gene Chr4:41661844-41662114 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0036571
ribozyme gene Chr4:47745975-47746245 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0037403
ribozyme gene Chr4:41240535-41240805 (-)
PWK/PhJ MGP_PWKPhJ_G0035347
ribozyme gene Chr4:40087415-40087685 (-)
SPRET/EiJ MGP_SPRETEiJ_G0035162
ribozyme gene Chr4:40827929-40828199 (-)
WSB/EiJ MGP_WSBEiJ_G0035856
ribozyme gene Chr4:41142287-41142557 (-)



Homology
more
  • Human Ortholog
    RMRP, RNA component of mitochondrial RNA processing endoribonuclease
  • Human Ortholog
    RMRP, RNA component of mitochondrial RNA processing endoribonuclease
    Orthology source: HGNC
  • Synonyms
    CHH, NME1, RMRPR, RRP2
  • Links
    NCBI Gene ID: 6023

  • Chr Location
    9p13.3; chr9:35657751-35658018 (-)  GRCh38.p7

  • HCOP
    human homology predictions: RMRP
Human Diseases
more
  • Diseases
    2 with human RMRP associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 2 alleles in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit complete embryonic lethality.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 19782 NCBI Gene Model | MGI Sequence Detail 275 C57BL/6J ±  kb
transcript NR_001460 RefSeq | MGI Sequence Detail 275 Not Specified  
For the selected sequence
Molecular
Reagents
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  • All nucleic 4
    Genomic 1
    cDNA 1
    Primer pair 1
    Other 1

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-13907, MGD-MRK-13908
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:12493 Hsieh CL, et al., The gene for the RNA component of the mitochondrial RNA-processing endoribonuclease is located on human Chromosome 9p and on mouse Chromosome 4. Cytogenet Cell Genet. 1989;51:1016
  • Latest
    J:228279 Huang W, et al., DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. 2015 Dec 24;528(7583):517-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory