Rnase1
Gene Detail

Symbol Name ID

Rnase1 ribonuclease, RNase A family, 1 (pancreatic) MGI:97919

Synonyms

Rib1, Rib-1

Feature Type

protein coding gene

Genetic Map

Chromosome 14

26.40 cM, cytoband B-C1
Detailed Genetic Map ± 1 cM


Mapping data(26)

Sequence Map

Chr14:51145002-51146767 bp, - strand From NCBI annotation of GRCm38   1766 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7919  Vertebrate Homology Class
1 human; 1 mouse; 3 rat; 1 chimpanzee; 1 rhesus macaque; 3 cattle; 1 dog

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Rnase1

Human homologs

Human Homolog		RNASE1, ribonuclease, RNase A family, 1 (pancreatic)
NCBI Gene ID		6035
neXtProt AC		NX_P07998
Human Synonyms		RIB1, RNS1
Human Chr (Location)		14q11.2; chr14:21269515-21271036 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Component	extracellular region
Function	endonuclease activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (49)    Tissues (48)    Images (2)
Theiler Stages: 23, 28

Assay Type	Results
RT-PCR	49

cDNA source data(137)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(144) Genomic(3) cDNA(139) Primer pair(2)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000035896 (Evidence)
Entrez Gene	19752 (Evidence)
UniGene	235538
DFCI	TC1572734
DoTS	DT.40158107
NIA Mouse Gene Index	U035522
EC	3.1.27.5
PDB	3TSR
Consensus CDS Project	CCDS27038.1
International Mouse Knockout Project Status	Rnase1

Sequences

Length	Strain/Species
genomic	19752	NCBI Gene Model | MGI Sequence Detail	1766	C57BL/6J
transcript	NM_011271	RefSeq | MGI Sequence Detail	977	C57BL/6
polypeptide	P00683	UniProt | EBI | MGI Sequence Detail	149	Not Applicable

All sequences(19) RefSeq(2) UniProt(3)

Polymorphisms

RFLP(5) : SNPs(26 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001427	Ribonuclease A
InterPro	IPR023411	Ribonuclease A, active site
InterPro	IPR023412	Ribonuclease A, domain
Protein Ontology	PR:000014042	ribonuclease pancreatic

Graphical View of Protein Domain Structure

References

(Earliest) J:8319 Elliott RW, et al., Assignment of pancreatic ribonuclease gene to mouse chromosome 14. Cytogenet Cell Genet. 1986;42(1-2):110-2
(Latest) J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
All references(49)

Other accession IDs

MGD-MRK-13876, MGD-MRK-13877, MGI:2145673