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Rbp3
Gene Detail
 Symbol
Name
ID
Rbp3
retinol binding protein 3, interstitial
MGI:97878
Synonyms Irbp, Rbp-3
Feature Type protein coding gene
Genetic Map
Chromosome 14
20.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr14:33954022-33964216 bp, + strand
From NCBI annotation of GRCm38

  10195 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9261  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: retinol-binding protein 3
Gene Tree: Rbp3

Human
homologs
Human Homolog RBP3, retinol binding protein 3, interstitial
NCBI Gene ID 5949
neXtProt AC  NX_P10745
Human Synonyms  D10S64, D10S65, D10S66, IRBP, RBPI, RP66
Human Chr (Location)  10q11.2; chr10:47348371-47357875 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human RBP3
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene experience photoreceptor degeneration.
 
Interactions
Rbp3 interacts with 222 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process proteolysis, transport
Component extracellular region, extracellular space, ...
Function retinal binding, retinol binding, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (52)    Tissues (25)    Images (15)
Theiler Stages: 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28
Assay TypeResults
RNA in situ 14
RT-PCR 20
RNase protection 18
cDNA source data(122)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(134) Genomic(5) cDNA(127) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000041534 (Evidence)
Entrez Gene19661 (Evidence)
UniGene436622
DFCITC1576379
DoTSDT.55209710
Consensus CDS ProjectCCDS26929.1
International Mouse Knockout Project StatusRbp3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 19661 NCBI Gene Model | MGI Sequence Detail 10195 C57BL/6J ±  kb
transcript NM_015745 RefSeq | MGI Sequence Detail 5276 C57BL/6 
polypeptide P49194 UniProt | EBI | MGI Sequence Detail 1234 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms RFLP(4) : SNPs within 2kb(242 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005151 Interphotoreceptor retinol-binding
Protein Ontology PR:000013820 retinol-binding protein 3
Graphical View of Protein Domain Structure
References (Earliest) J:12496 Kozak C, et al., Chromosome assignment in the mouse of the genes for several proteins involved in visual transduction. Cytogenet Cell Genet. 1989;51:1025-1026
(Latest) J:204200 Sato K, et al., Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein. J Neurosci. 2013 Oct 30;33(44):17458-68
All references(62)
Other
accession IDs
MGD-MRK-11462, MGD-MRK-13789, MGD-MRK-13794

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory