Rbp3
Gene Detail

Symbol Name ID

Rbp3 retinol binding protein 3, interstitial MGI:97878

Synonyms

Irbp, Rbp-3

Feature Type

protein coding gene

Genetic Map

Chromosome 14

20.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)

Sequence Map

Chr14:33954022-33964216 bp, + strand From NCBI annotation of GRCm38   10195 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9261  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: retinol-binding protein 3
Gene Tree: Rbp3

Human homologs

Human Homolog		RBP3, retinol binding protein 3, interstitial
NCBI Gene ID		5949
neXtProt AC		NX_P10745
Human Synonyms		D10S64, D10S65, D10S66, IRBP, RBPI
Human Chr (Location)		10q11.2; chr10:48381487-48390991 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human RBP3

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Mice homozygous for disruptions in this gene experience photoreceptor degeneration.

 

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	proteolysis, transport
Component	extracellular region, interphotoreceptor matrix, ...
Function	retinal binding, retinol binding, ...

External Resources: FuncBase

Expression

Literature Summary: (8 records)
Data Summary: Results (52)    Tissues (22)    Images (15)
Theiler Stages: 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	14
RT-PCR	20
RNase protection	18

cDNA source data(121)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(133) Genomic(5) cDNA(126) Primer pair(1) Other(1)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000041534 (Evidence)
Entrez Gene	19661 (Evidence)
UniGene	436622
DFCI	TC1576379
DoTS	DT.55209710
Consensus CDS Project	CCDS26929.1
International Mouse Knockout Project Status	Rbp3

Sequences

Length	Strain/Species
genomic	19661	NCBI Gene Model | MGI Sequence Detail	10195	C57BL/6J
transcript	NM_015745	RefSeq | MGI Sequence Detail	5276	C57BL/6
polypeptide	P49194	UniProt | EBI | MGI Sequence Detail	1234	Not Applicable

All sequences(19) RefSeq(2) UniProt(1)

Polymorphisms

RFLP(4) : SNPs(204 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005151	Interphotoreceptor retinol-binding
InterPro	IPR024591	Interphotoreceptor retinol-binding, N-terminal
Protein Ontology	PR:000013820	retinol-binding protein 3

Graphical View of Protein Domain Structure

References

(Earliest) J:12496 Kozak C, et al., Chromosome assignment in the mouse of the genes for several proteins involved in visual transduction. Cytogenet Cell Genet. 1989;51:1025-1026
(Latest) J:184783 Taniguchi RT, et al., Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7847-52
All references(60)

Other accession IDs

MGD-MRK-11462, MGD-MRK-13789, MGD-MRK-13794