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Rarg Gene Detail
Summary
  • Symbol
    Rarg
  • Name
    retinoic acid receptor, gamma
  • Synonyms
    MGC:11555, MGC:18523, RARgamma2, RAR gamma 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:97858
    NCBI Gene: 19411
  • Gene Overview
    MyGene.info: RARG
Location & Maps
more
  • Sequence Map
    Chr15:102234938-102257517 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      22580 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.40 cM, cytoband E-F3
  • Mapping Data
    14 experiments
Homology
more
  • Human Ortholog
    RARG, retinoic acid receptor gamma
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RARG, retinoic acid receptor gamma
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NR1B3, RARC
  • Links
    NCBI Gene ID: 5916
    neXtProt AC: NX_P13631
    UniProt: P13631

  • Chr Location
    12q13.13; chr12:53210566-53232256 (-)  GRCh38.p7
Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    42 phenotypes from 6 alleles in 7 genetic backgrounds
    100 phenotypes from multigenic genotypes
    73 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for targeted null mutations exhibit stunted growth, homeotic transformations of the rostral axial skeleton and tracheal cartilage, Harderian gland agenesis, high postnatal mortality, and male sterility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    74
  • GO References
    22
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    944
  • Tissues
    430
  • cDNA Data
    78
  • Literature Summary
    79
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029220 VEGA Gene Model | MGI Sequence Detail 22580 C57BL/6J ±  kb
transcript OTTMUST00000072430 VEGA | MGI Sequence Detail 2953 Not Applicable  
polypeptide OTTMUSP00000037288 VEGA | MGI Sequence Detail 458 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    138 from dbSNP Build 142
  • RFLP
    7
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 101
    Genomic 2
    cDNA 86
    Primer pair 12
    Other 1

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-13768, MGI:2145988
References
more
  • Summaries
    All 224
    Developmental Gene Expression 79
    Diseases 1
    Gene Ontology 22
    Phenotypes 73
  • Earliest
    J:13437 Bangham JW, Hairy ears, Eh. Mouse News Lett. 1965;33:68
  • Latest
    J:239682 Wilde JJ, et al., Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling. J Neurosci. 2017 Mar 08;37(10):2565-2579
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
07/11/2017
MGI 6.10 		The Jackson Laboratory