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Rarg Gene Detail
Summary
  • Symbol
    Rarg
  • Name
    retinoic acid receptor, gamma
  • Synonyms
    MGC:11555, MGC:18523, RAR gamma 2, RARgamma2
  • Feature Type
    protein coding gene
  • IDs
    MGI:97858
    NCBI Gene: 19411
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:102143373-102165891 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.40 cM, cytoband E-F3
  • Mapping Data
    14 experiments
Strain
Comparison
more
  • SNPs within 2kb
    492 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97858
 protein coding gene Chr15:102143373-102165952 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022405
 protein coding gene Chr15:104391006-104416889 (-)
A/J MGP_AJ_G0022367
 protein coding gene Chr15:100294388-100316890 (-)
AKR/J MGP_AKRJ_G0022342
 protein coding gene Chr15:103326372-103350369 (-)
BALB/cJ MGP_BALBcJ_G0022371
 protein coding gene Chr15:100338642-100361954 (-)
C3H/HeJ MGP_C3HHeJ_G0022138
 protein coding gene Chr15:103403639-103428394 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022820
 protein coding gene Chr15:108271034-108296322 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020343
 protein coding gene Chr15:96071091-96093822 (-)
CAST/EiJ MGP_CASTEiJ_G0021664
 protein coding gene Chr15:104268906-104292773 (-)
CBA/J MGP_CBAJ_G0022107
 protein coding gene Chr15:112066441-112096014 (-)
DBA/2J MGP_DBA2J_G0022238
 protein coding gene Chr15:99582604-99605160 (-)
FVB/NJ MGP_FVBNJ_G0022214
 protein coding gene Chr15:98643761-98666745 (-)
LP/J MGP_LPJ_G0022307
 protein coding gene Chr15:104553432-104577076 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022236
 protein coding gene Chr15:115645724-115670800 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022832
 protein coding gene Chr15:103353528-103378781 (-)
PWK/PhJ MGP_PWKPhJ_G0021404
 protein coding gene Chr15:99733586-99756715 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021236
 protein coding gene Chr15:103202818-103231560 (-)
WSB/EiJ MGP_WSBEiJ_G0021714
 protein coding gene Chr15:103985334-104010420 (-)



Homology
more
  • Human Ortholog
    RARG, retinoic acid receptor gamma
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RARG, retinoic acid receptor gamma
  • Synonyms
    NR1B3, RARC, RARgamma
  • Links
    NCBI Gene ID: 5916
    UniProt: P13631

  • Chr Location
    12q13.13; chr12:53210567-53232980 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    44 phenotypes from 6 alleles in 7 genetic backgrounds
    183 phenotypes from multigenic genotypes
    83 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for targeted null mutations exhibit stunted growth, homeotic transformations of the rostral axial skeleton and tracheal cartilage, Harderian gland agenesis, high postnatal mortality, and male sterility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    131
  • GO References
    27
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1783
  • Tissues
    508
  • cDNA Data
    79
  • Literature Summary
    99
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19411 NCBI Gene Model | MGI Sequence Detail 22519 C57BL/6J ±  kb
    transcript NM_011244 RefSeq | MGI Sequence Detail 2892 ZRU/MplStud  
    polypeptide P18911 UniProt | EBI | MGI Sequence Detail 458 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 125
      Genomic 2
      cDNA 87
      Primer pair 18
      Other 18

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-13768, MGI:2145988
    References
    more
    • Summaries
      All 268
      Developmental Gene Expression 99
      Diseases 1
      Gene Ontology 27
      Phenotypes 83
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:364193 Yin Y, et al., Retinoic acid antagonizes estrogen signaling to maintain adult uterine cell fate. Proc Natl Acad Sci U S A. 2025 Feb 4;122(5):e2416089122
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/18/2025
    MGI 6.24     		The Jackson Laboratory