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Rarg
Gene Detail
Symbol

Name
ID
Rarg
retinoic acid receptor, gamma
MGI:97858
Synonyms
MGC:11555, MGC:18523, RARgamma2, RAR gamma 2
Feature Type
protein coding gene
Genetic Map
Chromosome 15
57.40 cM, cytoband E-F3
Detailed Genetic Map ± 1 cM


Mapping data(14)
Sequence Map
Chr15:102234938-102257517 bp, - strand
From VEGA annotation of GRCm38

  22580 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20263  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: retinoic acid receptor
Gene Tree: Rarg

Human
homologs
Human Homolog RARG, retinoic acid receptor, gamma
NCBI Gene ID 5916
neXtProt AC  NX_P13631
Human Synonyms  NR1B3, RARC
Human Chr (Location)  12q13; chr12:53210566-53232256 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(242) : Gene trapped(232) Radiation induced(1) Targeted(9)
Genomic Mutations involving Rarg (1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations exhibit stunted growth, homeotic transformations of the rostral axial skeleton and tracheal cartilage, Harderian gland agenesis, high postnatal mortality, and male sterility.
 
Interactions
Rarg interacts with 230 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (74 annotations)
Process anterior/posterior pattern specification, bone development, ...
Component nuclear chromatin, nucleoplasm, ...
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (74 records)
Data Summary: Results (858)    Tissues (362)    Images (140)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 577
Northern blot 92
Western blot 14
RT-PCR 107
RNase protection 68
cDNA source data(77)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(100) Genomic(2) cDNA(85) Primer pair(12) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000029220 (Evidence)
Ensembl Gene ModelENSMUSG00000001288 (Evidence)
Entrez Gene19411 (Evidence)
UniGene1273
DFCITC1581855, TC1641167, TC1658895, TC1690872
DoTSDT.55165717, DT.87040403, DT.94147887, DT.94147888, DT.97359779
NIA Mouse Gene IndexU036693, U322973
Consensus CDS ProjectCCDS27875.1, CCDS37226.1
International Mouse Knockout Project StatusRarg
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029220 VEGA Gene Model | MGI Sequence Detail 22580 C57BL/6J ±  kb
transcript OTTMUST00000072430 VEGA | MGI Sequence Detail 2953 Not Applicable 
polypeptide OTTMUSP00000037288 VEGA | MGI Sequence Detail 458 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(8) UniProt(3)
Polymorphisms
RFLP(7) : SNPs within 2kb(183 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008946 Nuclear hormone receptor, ligand-binding
InterPro IPR000536 Nuclear hormone receptor, ligand-binding, core
InterPro IPR003078 Retinoic acid receptor
InterPro IPR001723 Steroid hormone receptor
InterPro IPR013088 Zinc finger, NHR/GATA-type
InterPro IPR001628 Zinc finger, nuclear hormone receptor-type
Protein Ontology PR:000013738 retinoic acid receptor gamma
References
(Earliest) J:9853 Harada M, et al., Strain difference and mode of inheritance of the susceptibility to passive cutaneous anaphylaxis mediated by allogeneic IgE antibody in the mouse. Immunol Invest. 1989 Jun;18(5):723-35
(Latest) J:214109 Adams MK, et al., The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis. J Biol Chem. 2014 May 23;289(21):14868-80
All references(203)
Other
accession IDs
MGD-MRK-13768, MGI:2145988

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory