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Rarg Gene Detail
Summary
  • Symbol
    Rarg
  • Name
    retinoic acid receptor, gamma
  • Synonyms
    MGC:11555, MGC:18523, RARgamma2, RAR gamma 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:97858
    NCBI Gene: 19411
  • Gene Overview
    MyGene.info: RARG
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:102234938-102257517 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.40 cM, cytoband E-F3
  • Mapping Data
    14 experiments
Strain
Comparison
more
  • SNPs within 2kb
    138 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97858
 protein coding gene Chr15:102234938-102257522 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022405
 protein coding gene Chr15:104391006-104416889 (-)
A/J MGP_AJ_G0022367
 protein coding gene Chr15:100294388-100316890 (-)
AKR/J MGP_AKRJ_G0022342
 protein coding gene Chr15:103326372-103350369 (-)
BALB/cJ MGP_BALBcJ_G0022371
 protein coding gene Chr15:100338642-100361954 (-)
C3H/HeJ MGP_C3HHeJ_G0022138
 protein coding gene Chr15:103403639-103428394 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022820
 protein coding gene Chr15:108271034-108296322 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020343
 protein coding gene Chr15:96071091-96093822 (-)
CAST/EiJ MGP_CASTEiJ_G0021664
 protein coding gene Chr15:104268906-104292773 (-)
CBA/J MGP_CBAJ_G0022107
 protein coding gene Chr15:112066441-112096014 (-)
DBA/2J MGP_DBA2J_G0022238
 protein coding gene Chr15:99582604-99605160 (-)
FVB/NJ MGP_FVBNJ_G0022214
 protein coding gene Chr15:98643761-98666745 (-)
LP/J MGP_LPJ_G0022307
 protein coding gene Chr15:104553432-104577076 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022236
 protein coding gene Chr15:115645724-115670800 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022832
 protein coding gene Chr15:103353528-103378781 (-)
PWK/PhJ MGP_PWKPhJ_G0021404
 protein coding gene Chr15:99733586-99756715 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021236
 protein coding gene Chr15:103202818-103231560 (-)
WSB/EiJ MGP_WSBEiJ_G0021714
 protein coding gene Chr15:103985334-104010420 (-)



Homology
more
  • Human Ortholog
    RARG, retinoic acid receptor gamma
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RARG, retinoic acid receptor gamma
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NR1B3, RARC
  • Links
    NCBI Gene ID: 5916
    neXtProt AC: NX_P13631
    UniProt: P13631

  • Chr Location
    12q13.13; chr12:53210566-53232256 (-)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    42 phenotypes from 6 alleles in 7 genetic backgrounds
    101 phenotypes from multigenic genotypes
    75 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygotes for targeted null mutations exhibit stunted growth, homeotic transformations of the rostral axial skeleton and tracheal cartilage, Harderian gland agenesis, high postnatal mortality, and male sterility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    92
  • GO References
    24
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1012
  • Tissues
    470
  • cDNA Data
    79
  • Literature Summary
    86
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000001288 Ensembl Gene Model | MGI Sequence Detail 22580 C57BL/6J ±  kb
    transcript ENSMUST00000043172 Ensembl | MGI Sequence Detail 2953 Not Applicable  
    polypeptide ENSMUSP00000048838 Ensembl | MGI Sequence Detail 458 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 102
      Genomic 2
      cDNA 87
      Primer pair 12
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-13768, MGI:2145988
    References
    more
    • Summaries
      All 243
      Developmental Gene Expression 86
      Diseases 1
      Gene Ontology 24
      Phenotypes 75
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:267106 Laursen KB, et al., Combinatorial knockout of RARalpha, RARbeta, and RARgamma completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells. J Biol Chem. 2018 Jul 27;293(30):11891-11900
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    05/14/2019
    MGI 6.14     		The Jackson Laboratory