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Rap2a
Gene Detail
 Symbol
Name
ID
Rap2a
RAS related protein 2a
MGI:97855
Synonyms 5830461H18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 14
64.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:120503601-120507194 bp, + strand
From VEGA annotation of GRCm38

  3594 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10875  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: ras protein
Gene Tree: Rap2a

Human
homologs
Human Homolog RAP2A, RAP2A, member of RAS oncogene family
NCBI Gene ID 5911
neXtProt AC  NX_P10114
Human Synonyms  KREV, K-REV, RAP2, RbBP-30
Human Chr (Location)  13q34; chr13:97434221-97467998 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rap2a interacts with 303 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process actin cytoskeleton reorganization, cellular protein localization, ...
Component cytosol, endosome, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(92)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(93) cDNA(93)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000017002 (Evidence)
Ensembl Gene ModelENSMUSG00000051615 (Evidence)
Entrez Gene76108 (Evidence)
UniGene261448
DFCITC1586008, TC1631837
DoTSDT.489009, DT.87053602
NIA Mouse Gene IndexU015983
Consensus CDS ProjectCCDS27341.1
International Mouse Knockout Project StatusRap2a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017002 VEGA Gene Model | MGI Sequence Detail 3594 C57BL/6J ±  kb
transcript OTTMUST00000041224 VEGA | MGI Sequence Detail 3594 Not Applicable 
polypeptide OTTMUSP00000018473 VEGA | MGI Sequence Detail 79 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(315 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013723 ras-related protein Rap-2a
References (Earliest) J:14384 Copeland NG, et al., A genetic linkage map of the mouse: current applications and future prospects [see comments]. Science. 1993 Oct 1;262(5130):57-66
(Latest) J:164745 Kawabe H, et al., Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron. 2010 Feb 11;65(3):358-72
All references(33)
Other
accession IDs
MGD-MRK-13764, MGI:1923358

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory