Rap2a
Gene Detail

Symbol

Name
ID

Rap2a
RAS related protein 2a
MGI:97855

Synonyms

5830461H18Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 14
64.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr14:120503601-120507194 bp, + strand From VEGA annotation of GRCm38   3594 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:10875  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: ras protein
Gene Tree: Rap2a

Human
homologs

Human Homolog		RAP2A, RAP2A, member of RAS oncogene family
NCBI Gene ID		5911
neXtProt AC		NX_P10114
Human Synonyms		KREV, K-REV, RAP2, RbBP-30
Human Chr (Location)		13q34; chr13:97434221-97467998 (+)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(2) : Gene trapped(2)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Rap2a interacts with 303 markers (Mir7-1, Mir7-2, Mir7b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (30 annotations)

Process	actin cytoskeleton reorganization, cellular protein localization, ...
Component	cytosol, endosome, ...
Function	GTPase activity, GTP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)

cDNA source data(92)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(93) cDNA(93)
Microarray probesets(5)

Other database
links

VEGA Gene Model	OTTMUSG00000017002 (Evidence)
Ensembl Gene Model	ENSMUSG00000051615 (Evidence)
Entrez Gene	76108 (Evidence)
UniGene	261448
DFCI	TC1586008, TC1631837
DoTS	DT.489009, DT.87053602
NIA Mouse Gene Index	U015983
Consensus CDS Project	CCDS27341.1
International Mouse Knockout Project Status	Rap2a

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017002	VEGA Gene Model | MGI Sequence Detail	3594	C57BL/6J
transcript	OTTMUST00000041224	VEGA | MGI Sequence Detail	3594	Not Applicable
polypeptide	OTTMUSP00000018473	VEGA | MGI Sequence Detail	79	Not Applicable

All sequences(30) RefSeq(2) UniProt(2)

Polymorphisms

RFLP(1) : SNPs within 2kb(315 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR027417	P-loop containing nucleoside triphosphate hydrolase
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR020849	Small GTPase superfamily, Ras type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013723	ras-related protein Rap-2a

References

(Earliest) J:14384 Copeland NG, et al., A genetic linkage map of the mouse: current applications and future prospects [see comments]. Science. 1993 Oct 1;262(5130):57-66
(Latest) J:164745 Kawabe H, et al., Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron. 2010 Feb 11;65(3):358-72
All references(33)

Other
accession IDs

MGD-MRK-13764, MGI:1923358