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Rap2a Gene Detail
Summary
  • Symbol
    Rap2a
  • Name
    RAS related protein 2a
  • Synonyms
    5830461H18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:97855
    NCBI Gene: 76108
  • Gene Overview
    MyGene.info: RAP2A
Location & Maps
more
  • Sequence Map
    Chr14:120503601-120507194 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3594 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    RAP2A, RAP2A, member of RAS oncogene family
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RAP2A, RAP2A, member of RAS oncogene family
    Orthology source: HomoloGene
  • Synonyms
    KREV, K-REV, RAP2, RbBP-30
  • Links
    NCBI Gene ID: 5911
    neXtProt AC: NX_P10114

  • Chr Location
    13q34; chr13:97434221-97467998 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Rap2a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017002 VEGA Gene Model | MGI Sequence Detail 3594 C57BL/6J ±  kb
transcript OTTMUST00000041224 VEGA | MGI Sequence Detail 3594 Not Applicable  
polypeptide OTTMUSP00000018473 VEGA | MGI Sequence Detail 79 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    312 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013723 ras-related protein Rap-2a
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR020849 Small GTPase superfamily, Ras type
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
less
  • All nucleic 93
    cDNA 93

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-13764, MGI:1923358
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:14384 Copeland NG, et al., A genetic linkage map of the mouse: current applications and future prospects [see comments]. Science. 1993 Oct 1;262(5130):57-66
  • Latest
    J:164745 Kawabe H, et al., Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron. 2010 Feb 11;65(3):358-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory