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Rap2a Gene Detail
Summary
  • Symbol
    Rap2a
  • Name
    RAS related protein 2a
  • Synonyms
    5830461H18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:97855
    NCBI Gene: 76108
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:120715873-120744606 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 64.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    840 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97855
 protein coding gene Chr14:120715856-120744606 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021658
 protein coding gene Chr14:118195126-118228893 (+)
A/J MGP_AJ_G0021618
 protein coding gene Chr14:113675318-113705359 (+)
AKR/J MGP_AKRJ_G0021594
 protein coding gene Chr14:117339691-117372976 (+)
BALB/cJ MGP_BALBcJ_G0021624
 protein coding gene Chr14:114208670-114240597 (+)
C3H/HeJ MGP_C3HHeJ_G0021402
 protein coding gene Chr14:117236028-117265248 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022064
 protein coding gene Chr14:122763680-122802329 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019602
 protein coding gene Chr14:109615376-109642875 (+)
CAST/EiJ MGP_CASTEiJ_G0020917
 protein coding gene Chr14:115102653-115128692 (+)
CBA/J MGP_CBAJ_G0021370
 protein coding gene Chr14:127452237-127490649 (+)
DBA/2J MGP_DBA2J_G0021493
 protein coding gene Chr14:113555864-113584751 (+)
FVB/NJ MGP_FVBNJ_G0021471
 protein coding gene Chr14:111861652-111896931 (+)
LP/J MGP_LPJ_G0021561
 protein coding gene Chr14:119185052-119218161 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021498
 protein coding gene Chr14:132504458-132536213 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022087
 protein coding gene Chr14:116871242-116907461 (+)
PWK/PhJ MGP_PWKPhJ_G0020661
 protein coding gene Chr14:110590877-110667169 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020499
 protein coding gene Chr14:113103179-113181457 (+)
WSB/EiJ MGP_WSBEiJ_G0020973
 protein coding gene Chr14:117615802-117646729 (+)



Homology
more
  • Human Ortholog
    RAP2A, RAP2A, member of RAS oncogene family
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAP2A, RAP2A, member of RAS oncogene family
  • Synonyms
    K-REV, KREV, RAP2, RbBP-30
  • Links
    NCBI Gene ID: 5911
    UniProt: P10114

  • Chr Location
    13q32.1; chr13:97434169-97469128 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Rap2a
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    15 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    92
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    93
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76108 NCBI Gene Model | MGI Sequence Detail 28734 C57BL/6J ±  kb
transcript NM_029519 RefSeq | MGI Sequence Detail 4174 ZRU/MplStud  
polypeptide Q80ZJ1 UniProt | EBI | MGI Sequence Detail 183 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 94
    cDNA 94

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-13764, MGI:1923358
References
more
  • Summaries
    All 45
    Developmental Gene Expression 1
    Gene Ontology 13
    Phenotypes 9
  • Earliest
    J:14384 Copeland NG, et al., A genetic linkage map of the mouse: current applications and future prospects [see comments]. Science. 1993 Oct 1;262(5130):57-66
  • Latest
    J:345166 Qi H, et al., Loss of RAP2A Aggravates Cartilage Degradation in TMJOA via YAP Signaling. J Dent Res. 2023 Mar;102(3):302-312
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory