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Raly Gene Detail
Summary
  • Symbol
    Raly
  • Name
    hnRNP-associated with lethal yellow
  • Synonyms
    Merc
  • Feature Type
    protein coding gene
  • IDs
    MGI:97850
    NCBI Gene: 19383
  • Gene Overview
    MyGene.info: RALY
Location & Maps
more
  • Sequence Map
    Chr2:154791096-154867261 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      76166 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 76.83 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RALY, RALY heterogeneous nuclear ribonucleoprotein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RALY, RALY heterogeneous nuclear ribonucleoprotein
    Orthology source: HomoloGene
  • Synonyms
    HNRPCL2, P542
  • Links
    NCBI Gene ID: 22913
    neXtProt AC: NX_Q9UKM9

  • Chr Location
    20q11.21-q11.23; chr20:33993652-34083185 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    24 phenotype references
  • All Mutations and Alleles
    2
  • Chemically and radiation induced
    1
  • Gene trapped
    1
  • Genomic Mutations
    1 involving Raly
  • Incidental Mutations
Mice homozygous for a gene trap allele are viable.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015980 VEGA Gene Model | MGI Sequence Detail 76166 C57BL/6J ±  kb
transcript OTTMUST00000038030 VEGA | MGI Sequence Detail 1802 Not Applicable  
polypeptide OTTMUSP00000017057 VEGA | MGI Sequence Detail 312 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    555 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000013701 RNA-binding protein Raly
  • InterPro Domains
    IPR017347 Heterogeneous nuclear ribonucleoprotein C
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
Molecular
Reagents
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  • All nucleic 29
    Genomic 8
    cDNA 17
    Primer pair 4

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-13758, MGI:2139040
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 24
  • Earliest
    J:12911 Michaud EJ, et al., The embryonic lethality of homozygous lethal yellow mice (Ay/Ay) is associated with the disruption of a novel RNA-binding protein. Genes Dev. 1993 Jul;7(7A):1203-13
  • Latest
    J:214754 Pohlmeier WE, et al., Progressive obesity alters the steroidogenic response to ovulatory stimulation and increases the abundance of mRNAs stored in the ovulated oocyte. Mol Reprod Dev. 2014 Aug;81(8):735-47

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory