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Rab3d
Gene Detail
Symbol

Name
ID
Rab3d
RAB3D, member RAS oncogene family
MGI:97844
Synonyms
C130057E11Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
7.91 cM, cytoband A2-A3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr9:21907491-21918192 bp, - strand
From VEGA annotation of GRCm38

  10702 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20902  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAB3D
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab3d

Human
homologs
RAB3D, RAB3D, member RAS oncogene family
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9545
neXtProt AC: NX_O95716

Human Synonyms: D2-2, GOV, RAB16, RAD3D

Human Chr (Location): 19p13.2; chr19:11322046-11339668 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(1) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene show no obvious phenotypic changes. Secretory granules in mast cells and some exocrine glands are double in volume however.
 
Interactions
Rab3d interacts with 255 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process exocytosis, intracellular protein transport, ...
Component endosome, extracellular exosome, ...
Function GTPase activity, GTPase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (78)    Tissues (9)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 78
cDNA source data(147)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rab3d    NEW 
Molecular
reagents
All nucleic(149) Genomic(1) cDNA(148)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000031911 (Evidence)
Ensembl Gene Model ENSMUSG00000019066 (Evidence)
Entrez Gene 19340 (Evidence)
UniGene 260157
DFCI TC1572904, TC1723310, TC1764997
DoTS DT.101248610, DT.91352006, DT.94360357, DT.94360360
NIA Mouse Gene Index U030593, U312105
Consensus CDS Project CCDS22912.1
International Mouse Phenotyping Consortium Status Rab3d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031911 VEGA Gene Model | MGI Sequence Detail 10702 C57BL/6J ±  kb
transcript OTTMUST00000079125 VEGA | MGI Sequence Detail 3886 Not Applicable 
polypeptide OTTMUSP00000042159 VEGA | MGI Sequence Detail 219 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(8) UniProt(5)
Polymorphisms
SNPs within 2kb(10 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013620 ras-related protein Rab-3D
References
(Earliest) J:1134 Baldini G, et al., Cloning of a Rab3 isotype predominantly expressed in adipocytes. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5049-52
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(51)
Other
accession IDs
MGD-MRK-13747, MGI:2442160

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory