Rab3d
Gene Detail

Symbol Name ID

Rab3d RAB3D, member RAS oncogene family MGI:97844

Synonyms

C130057E11Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 9

7.91 cM, cytoband A2-A3
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr9:21907491-21918192 bp, - strand From VEGA annotation of GRCm38   10702 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:20902  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab3d

Human homologs

Human Homolog		RAB3D, RAB3D, member RAS oncogene family
NCBI Gene ID		9545
neXtProt AC		NX_O95716
Human Synonyms		D2-2, GOV, RAB16, RAD3D
Human Chr (Location)		19p13.2; chr19:11432722-11450344 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(7) : Targeted(6) Gene trapped(1)
 

Mice homozygous for disruptions in this gene show no obvious phenotypic changes. Secretory granules in mast cells and some exocrine glands are double in volume however.

 

Gene Ontology (GO) classifications

All GO classifications: (18 annotations)

Process	exocytosis, peptidyl-cysteine methylation, ...
Component	membrane, mitochondrion, ...
Function	GTPase binding, GTP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (78)    Tissues (9)    Images (24)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	78

cDNA source data(133)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(135) Genomic(1) cDNA(134)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000031911 (Evidence)
Ensembl Gene Model	ENSMUSG00000019066 (Evidence)
Entrez Gene	19340 (Evidence)
UniGene	260157
DFCI	TC1572904, TC1723310, TC1764997
DoTS	DT.101248610, DT.91352006, DT.94360357, DT.94360360
NIA Mouse Gene Index	U030593, U312105
Consensus CDS Project	CCDS22912.1
International Mouse Knockout Project Status	Rab3d

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031911	VEGA Gene Model | MGI Sequence Detail	10702	C57BL/6J
transcript	OTTMUST00000079124	VEGA | MGI Sequence Detail	3835	Not Applicable
polypeptide	OTTMUSP00000042158	VEGA | MGI Sequence Detail	219	Not Applicable

All sequences(57) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(9 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013620	ras-related protein Rab-3D

References

(Earliest) J:1134 Baldini G, et al., Cloning of a Rab3 isotype predominantly expressed in adipocytes. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5049-52
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(51)

Other accession IDs

MGD-MRK-13747, MGI:2442160