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Rab3d Gene Detail
Summary
  • Symbol
    Rab3d
  • Name
    RAB3D, member RAS oncogene family
  • Synonyms
    C130057E11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:97844
    NCBI Gene: 19340
  • Gene Overview
    MyGene.info: RAB3D
Location & Maps
more
  • Sequence Map
    Chr9:21907491-21918192 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10702 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 7.91 cM, cytoband A2-A3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    RAB3D, RAB3D, member RAS oncogene family
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RAB3D, RAB3D, member RAS oncogene family
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D2-2, GOV, RAB16, RAD3D
  • Links
    NCBI Gene ID: 9545
    neXtProt AC: NX_O95716

  • Chr Location
    19p13.2; chr19:11322046-11339668 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotypes from multigenic genotypes
    11 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    1
  • Targeted
    6
  • Incidental Mutations
Mice homozygous for disruptions in this gene show no obvious phenotypic changes. Secretory granules in mast cells and some exocrine glands are double in volume however.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031911 VEGA Gene Model | MGI Sequence Detail 10702 C57BL/6J ±  kb
transcript OTTMUST00000079124 VEGA | MGI Sequence Detail 3835 Not Applicable  
polypeptide OTTMUSP00000042158 VEGA | MGI Sequence Detail 219 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    10 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000013620 ras-related protein Rab-3D
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
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  • All nucleic 149
    Genomic 1
    cDNA 148

    Microarray probesets 7
Other
Accession IDs
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MGD-MRK-13747, MGI:2442160
References
more
  • Summaries
    All 49
    Developmental Gene Expression 5
    Gene Ontology 11
    Phenotypes 11
  • Earliest
    J:1134 Baldini G, et al., Cloning of a Rab3 isotype predominantly expressed in adipocytes. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5049-52
  • Latest
    J:233777 Ray JP, et al., The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity. 2015 Oct 20;43(4):690-702

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory