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Rab3d
Gene Detail
 Symbol
Name
ID
Rab3d
RAB3D, member RAS oncogene family
MGI:97844
Synonyms C130057E11Rik
Feature Type protein coding gene
Genetic Map
Chromosome 9
7.91 cM, cytoband A2-A3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr9:21907491-21918192 bp, - strand
From VEGA annotation of GRCm38

  10702 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20902  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab3d

Human
homologs
Human Homolog RAB3D, RAB3D, member RAS oncogene family
NCBI Gene ID 9545
neXtProt AC  NX_O95716
Human Synonyms  D2-2, GOV, RAB16, RAD3D
Human Chr (Location)  19p13.2; chr19:11322046-11339668 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(1) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene show no obvious phenotypic changes. Secretory granules in mast cells and some exocrine glands are double in volume however.
 
Interactions
Rab3d interacts with 255 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process exocytosis, peptidyl-cysteine methylation, ...
Component extracellular vesicular exosome, membrane, ...
Function GTPase binding, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (78)    Tissues (9)    Images (24)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 78
cDNA source data(147)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(149) Genomic(1) cDNA(148)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000031911 (Evidence)
Ensembl Gene ModelENSMUSG00000019066 (Evidence)
Entrez Gene19340 (Evidence)
UniGene260157
DFCITC1572904, TC1723310, TC1764997
DoTSDT.101248610, DT.91352006, DT.94360357, DT.94360360
NIA Mouse Gene IndexU030593, U312105
Consensus CDS ProjectCCDS22912.1
International Mouse Knockout Project StatusRab3d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031911 VEGA Gene Model | MGI Sequence Detail 10702 C57BL/6J ±  kb
transcript OTTMUST00000079124 VEGA | MGI Sequence Detail 3835 Not Applicable 
polypeptide OTTMUSP00000042158 VEGA | MGI Sequence Detail 219 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(4) UniProt(5)
Polymorphisms SNPs within 2kb(10 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013620 ras-related protein Rab-3D
References (Earliest) J:1134 Baldini G, et al., Cloning of a Rab3 isotype predominantly expressed in adipocytes. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5049-52
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(52)
Other
accession IDs
MGD-MRK-13747, MGI:2442160

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory