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Pygb Gene Detail
Summary
  • Symbol
    Pygb
  • Name
    brain glycogen phosphorylase
  • Synonyms
    MGC:36329
  • Feature Type
    protein coding gene
  • IDs
    MGI:97828
    NCBI Gene: 110078
Location & Maps
more
  • Sequence Map
    Chr2:150786735-150831758 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      45024 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 74.74 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    PYGB, phosphorylase, glycogen; brain
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PYGB, phosphorylase, glycogen; brain
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GPBB
  • Links
    NCBI Gene ID: 5834
    neXtProt AC: NX_P11216

  • Chr Location
    20p11.21; chr20:25248070-25298012 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    6
  • Genomic Mutations
    2 involving Pygb
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015772 VEGA Gene Model | MGI Sequence Detail 45024 C57BL/6J ±  kb
transcript OTTMUST00000037476 VEGA | MGI Sequence Detail 3909 Not Applicable  
polypeptide OTTMUSP00000016797 VEGA | MGI Sequence Detail 843 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    493 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000013520 glycogen phosphorylase, brain form
  • EC
  • InterPro Domains
    IPR011833 Glycogen/starch/alpha-glucan phosphorylase
    IPR000811 Glycosyl transferase, family 35
Molecular
Reagents
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  • All nucleic 178
    cDNA 177
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13701
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:10246 Glaser T, et al., Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively. Genomics. 1989 Oct;5(3):510-21
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory