Homozygous mutant mice die in mid-gestation or shortly after birth depending on genetic background, are small in size, have short limbs, and accelerated differentiation of chondrocytes resulting in accelerated bone mineralization.
|Process||adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, ...|
|Component||apical plasma membrane, basolateral plasma membrane, ...|
|Function||G-protein coupled receptor activity, parathyroid hormone receptor activity, ...|
|InterPro||IPR001879||GPCR, family 2, extracellular hormone receptor domain|
|InterPro||IPR017981||GPCR, family 2-like|
|InterPro||IPR002170||GPCR, family 2, parathyroid hormone receptor|
|InterPro||IPR000832||GPCR, family 2, secretin-like|
|InterPro||IPR017983||GPCR, family 2, secretin-like, conserved site|
|Protein Ontology||PR:000013430||parathyroid hormone/parathyroid hormone-related peptide receptor|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update