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Ptgfr
Gene Detail
Symbol

Name
ID
Ptgfr
prostaglandin F receptor
MGI:97796
Synonyms
FP, PGF
Feature Type
protein coding gene
Genetic Map
Chromosome 3
76.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:151798918-151837630 bp, - strand
From VEGA annotation of GRCm38

  38713 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:741  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog; 2 zebrafish

HCOP human homology predictions: PTGFR
Protein SuperFamily: G protein-coupled prostanoid receptor
Gene Tree: Ptgfr

Human
homologs
PTGFR, prostaglandin F receptor (FP)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 5737
neXtProt AC: NX_P43088

Human Synonyms: FP

Human Chr (Location): 1p31.1; chr1:78476240-78540701 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Pregnant females homozygous for a targeted null mutation are unable to deliver their offspring due to lack of induction of the oxytocin receptor and fail to show the normal decline of serum progesterone levels preceding parturition.
 
Interactions
Ptgfr interacts with 354 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Expression
Literature Summary: (4 records)
Data Summary: Results (100)    Tissues (36)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 100
cDNA source data(10)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ptgfr ; ZFIN ptgfr    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000025720 (Evidence)
Ensembl Gene Model ENSMUSG00000028036 (Evidence)
Entrez Gene 19220 (Evidence)
DFCI TC1584982, TC1614592
DoTS DT.40139867, DT.97363178
NIA Mouse Gene Index U024762
Consensus CDS Project CCDS17913.1
International Mouse Phenotyping Consortium Status Ptgfr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025720 VEGA Gene Model | MGI Sequence Detail 38713 C57BL/6J ±  kb
transcript OTTMUST00000063339 VEGA | MGI Sequence Detail 4208 Not Applicable 
polypeptide OTTMUSP00000031304 VEGA | MGI Sequence Detail 366 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(496 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001244 Prostaglandin DP receptor
InterPro IPR000141 Prostaglandin F receptor
InterPro IPR008365 Prostanoid receptor
Protein Ontology PR:000001660 prostaglandin F2-alpha receptor
References
(Earliest) J:16440 Sugimoto Y, et al., Cloning and expression of a cDNA for mouse prostaglandin F receptor. J Biol Chem. 1994 Jan 14;269(2):1356-60
(Latest) J:197334 Taketomi Y, et al., Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis. Nat Immunol. 2013 Jun;14(6):554-63
All references(58)
Other
accession IDs
MGD-MRK-13663, MGI:2139843

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory