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Ptgfr
Gene Detail
Symbol

Name
ID
Ptgfr
prostaglandin F receptor
MGI:97796
Synonyms
FP, PGF
Feature Type
protein coding gene
Genetic Map
Chromosome 3
76.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:151798918-151837630 bp, - strand
From VEGA annotation of GRCm38

  38713 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:741  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog; 2 zebrafish

Protein SuperFamily: G protein-coupled prostanoid receptor
Gene Tree: Ptgfr

Human
homologs
Human Homolog PTGFR, prostaglandin F receptor (FP)
NCBI Gene ID 5737
neXtProt AC  NX_P43088
Human Synonyms  FP
Human Chr (Location)  1p31.1; chr1:78476247-78540701 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Pregnant females homozygous for a targeted null mutation are unable to deliver their offspring due to lack of induction of the oxytocin receptor and fail to show the normal decline of serum progesterone levels preceding parturition.
 
Interactions
Ptgfr interacts with 354 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Expression
Literature Summary: (4 records)
Data Summary: Results (100)    Tissues (36)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 100
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000025720 (Evidence)
Ensembl Gene ModelENSMUSG00000028036 (Evidence)
Entrez Gene19220 (Evidence)
DFCITC1584982, TC1614592
DoTSDT.40139867, DT.97363178
NIA Mouse Gene IndexU024762
Consensus CDS ProjectCCDS17913.1
International Mouse Knockout Project StatusPtgfr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025720 VEGA Gene Model | MGI Sequence Detail 38713 C57BL/6J ±  kb
transcript OTTMUST00000063340 VEGA | MGI Sequence Detail 1535 Not Applicable 
polypeptide OTTMUSP00000031305 VEGA | MGI Sequence Detail 366 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(2) UniProt(7)
Polymorphisms
RFLP(1) : SNPs within 2kb(496 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001244 Prostaglandin DP receptor
InterPro IPR000141 Prostaglandin F receptor
InterPro IPR008365 Prostanoid receptor
Protein Ontology PR:000001660 prostaglandin F2-alpha receptor
References
(Earliest) J:16440 Sugimoto Y, et al., Cloning and expression of a cDNA for mouse prostaglandin F receptor. J Biol Chem. 1994 Jan 14;269(2):1356-60
(Latest) J:197334 Taketomi Y, et al., Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis. Nat Immunol. 2013 Jun;14(6):554-63
All references(60)
Other
accession IDs
MGD-MRK-13663, MGI:2139843

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory