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Psph
Gene Detail
Symbol

Name
ID
Psph
phosphoserine phosphatase
MGI:97788
Synonyms
PSPase
Feature Type
protein coding gene
Genetic Map
Chromosome 5
68.26 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:129765558-129787449 bp, - strand
From VEGA annotation of GRCm38

  21892 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31245  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PSPH
Gene Tree: Psph

Human
homologs
PSPH, phosphoserine phosphatase
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 5723
neXtProt AC: NX_P78330

Human Synonyms: PSP, PSPHD

Human Chr (Location): 7p11.2; chr7:56010363-56051604 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human PSPH

Mutations,
alleles, and
phenotypes
All mutations/alleles(42) : Gene trapped(38) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Psph interacts with 63 markers (Mir32, Mir33, Mir101a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cellular amino acid biosynthetic process, dephosphorylation, ...
Component cytoplasm, neuron projection
Function calcium ion binding, hydrolase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (204)    Tissues (111)    Images (33)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 204
cDNA source data(69)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase psph    NEW 
Molecular
reagents
All nucleic(70) cDNA(69) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000027654 (Evidence)
Ensembl Gene Model ENSMUSG00000029446 (Evidence)
Entrez Gene 100678 (Evidence)
UniGene 271784
DFCI TC1575345, TC1605957
NIA Mouse Gene Index U026765
EC 3.1.3.3
Consensus CDS Project CCDS19699.1
International Mouse Phenotyping Consortium Status Psph
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027654 VEGA Gene Model | MGI Sequence Detail 21892 C57BL/6J ±  kb
transcript OTTMUST00000068433 VEGA | MGI Sequence Detail 1733 Not Applicable 
polypeptide OTTMUSP00000034603 VEGA | MGI Sequence Detail 225 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(299 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023214 HAD-like domain
InterPro IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like
InterPro IPR023190 Phosphoserine phosphatase, domain 2
InterPro IPR004469 Phosphoserine phosphatase SerB
Protein Ontology PR:000013404 phosphoserine phosphatase
References
(Earliest) J:12272 Lalley PA, et al., Comparative gene mapping in the mouse involving genes assigned to human chromosomes 7 and 20. (Abstracts of meeting presentations: Human gene mapping 7, Los Angeles Conference (1983) Seventh International Workshop on Human Gene Mapping). Cytogenet Cell Genet. 1984;37 (1-4):514-515 (Abstr.) (399-616)
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(39)
Other
accession IDs
MGD-MRK-13654, MGI:2140913

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory