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Prm2 Gene Detail
Summary
  • Symbol
    Prm2
  • Name
    protamine 2
  • Synonyms
    Prm-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:97766
    NCBI Gene: 19119
Location & Maps
more
  • Sequence Map
    Chr16:10791380-10796134 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4755 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 5.84 cM
  • Mapping Data
    16 experiments
Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
In chimeras deformed sperm with loosely compacted chromatin are derived from spermatogenic cells with one copy of the mutated allele. No offspring carrying the mutated allele are produced from matings using chimeras.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048599 VEGA Gene Model | MGI Sequence Detail 4755 C57BL/6J ±  kb
transcript OTTMUST00000124502 VEGA | MGI Sequence Detail 621 Not Applicable  
polypeptide OTTMUSP00000067728 VEGA | MGI Sequence Detail 107 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    68 from dbSNP Build 142
Protein
Information
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Molecular
Reagents
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  • All nucleic 366
    Genomic 6
    cDNA 357
    Primer pair 2
    Other 1

    Microarray probesets 2
Other
Accession IDs
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MGD-MRK-13617, MGD-MRK-13619, MGI:2146456
References
more
  • Summaries
    All 61
    Developmental Gene Expression 8
    Gene Ontology 8
    Phenotypes 3
  • Earliest
    J:7131 Kleene KC, et al., cDNA clones encoding cytoplasmic poly(A)+ RNAs which first appear at detectable levels in haploid phases of spermatogenesis in the mouse. Dev Biol. 1983 Aug;98(2):455-64
  • Latest
    J:203763 Fukuda N, et al., The transacting factor CBF-A/Hnrnpab binds to the A2RE/RTS element of protamine 2 mRNA and contributes to its translational regulation during mouse spermatogenesis. PLoS Genet. 2013;9(10):e1003858

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory