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Prm2
Gene Detail
Symbol

Name
ID
Prm2
protamine 2
MGI:97766
Synonyms
Prm-2
Feature Type
protein coding gene
Genetic Map
Chromosome 16
5.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(16)
Sequence Map
Chr16:10791380-10796134 bp, - strand
From VEGA annotation of GRCm38

  4755 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Prm2
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
In chimeras deformed sperm with loosely compacted chromatin are derived from spermatogenic cells with one copy of the mutated allele. No offspring carrying the mutated allele are produced from matings using chimeras.
 
Interactions
Prm2 interacts with 35 markers (Mir1a-1, Mir1a-2, Mir24-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cell differentiation, chromosome condensation, ...
Component chromosome, nucleosome, ...
Function DNA binding
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (6)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 6
cDNA source data(357)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(365) Genomic(6) cDNA(357) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000048599 (Evidence)
Ensembl Gene ModelENSMUSG00000038015 (Evidence)
Entrez Gene19119 (Evidence)
UniGene325769
DFCITC1571940
DoTSDT.101404889, DT.496640
NIA Mouse Gene IndexU036785
Consensus CDS ProjectCCDS27955.1
International Mouse Knockout Project StatusPrm2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048599 VEGA Gene Model | MGI Sequence Detail 4755 C57BL/6J ±  kb
transcript OTTMUST00000124502 VEGA | MGI Sequence Detail 621 Not Applicable 
polypeptide OTTMUSP00000067728 VEGA | MGI Sequence Detail 107 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(3)
Polymorphisms
RFLP(15) : SNPs within 2kb(81 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000492 Protamine 2, PRM2
Protein Ontology PR:000013250 protamine-2
References
(Earliest) J:7131 Kleene KC, et al., cDNA clones encoding cytoplasmic poly(A)+ RNAs which first appear at detectable levels in haploid phases of spermatogenesis in the mouse. Dev Biol. 1983 Aug;98(2):455-64
(Latest) J:203763 Fukuda N, et al., The transacting factor CBF-A/Hnrnpab binds to the A2RE/RTS element of protamine 2 mRNA and contributes to its translational regulation during mouse spermatogenesis. PLoS Genet. 2013;9(10):e1003858
All references(66)
Other
accession IDs
MGD-MRK-13617, MGD-MRK-13619, MGI:2146456

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory