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Prim2
Gene Detail
 Symbol
Name
ID
Prim2
DNA primase, p58 subunit
MGI:97758
Feature Type protein coding gene
Genetic Map
Chromosome 1
12.70 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr1:33453811-33669758 bp, - strand
From NCBI annotation of GRCm38

  215948 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:731  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: DNA primase, large subunit
Gene Tree: Prim2

Human
homologs
Human Homolog PRIM2, primase, DNA, polypeptide 2 (58kDa)
NCBI Gene ID 5558
neXtProt AC  NX_P49643
Human Synonyms  p58, PRIM2A
Human Chr (Location)  6p12-p11.1; chr6:57314805-57646850 (+)  GRCh38
Alleles
and
phenotypes
All alleles(27) : Gene trapped(25) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process DNA replication, DNA replication, synthesis of RNA primer, ...
Component primosome complex
Function 4 iron, 4 sulfur cluster binding, ATP:coenzyme F420 adenylyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (344)    Tissues (110)    Images (59)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 344
cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000026134 (Evidence)
Entrez Gene19076 (Evidence)
DFCITC1575510
DoTSDT.101327199, DT.101358086, DT.492312
NIA Mouse Gene IndexU021208
EC2.7.7.-
Consensus CDS ProjectCCDS14862.1
International Mouse Knockout Project StatusPrim2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 19076 NCBI Gene Model | MGI Sequence Detail 215948 C57BL/6J ±  kb
transcript NM_008922 RefSeq | MGI Sequence Detail 1990 C57BL/6 
polypeptide P33610 UniProt | EBI | MGI Sequence Detail 505 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(16) UniProt(3)
Polymorphisms SNPs within 2kb(1392 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1424)
Protein-related
information
ResourceIDDescription
InterPro IPR016558 DNA primase, large subunit, eukaryotic
InterPro IPR007238 DNA primase large subunit, eukaryotic/archaeal
Protein Ontology PR:000013216 DNA primase large subunit
Graphical View of Protein Domain Structure
References (Earliest) J:22339 Prussak CE, et al., Mouse primase p49 subunit molecular cloning indicates conserved and divergent regions. J Biol Chem. 1989 Mar 25;264(9):4957-63
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)
Other
accession IDs
MGD-MRK-13609, MGI:2138206

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory