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Ppic Gene Detail
Summary
  • Symbol
    Ppic
  • Name
    peptidylprolyl isomerase C
  • Synonyms
    cyclophilin C, CyP-20c
  • Feature Type
    protein coding gene
  • IDs
    MGI:97751
    NCBI Gene: 19038
  • Gene Overview
    MyGene.info: PPIC
Location & Maps
more
  • Sequence Map
    Chr18:53406341-53418007 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11667 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 29.03 cM, cytoband D1
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    PPIC, peptidylprolyl isomerase C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PPIC, peptidylprolyl isomerase C
    Orthology source: HomoloGene
  • Synonyms
    CYPC
  • Links
    NCBI Gene ID: 5480
    neXtProt AC: NX_P45877

  • Chr Location
    5q23.2; chr5:123023383-123036730 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    2
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19038 NCBI Gene Model | MGI Sequence Detail 11667 C57BL/6J ±  kb
transcript NM_008908 RefSeq | MGI Sequence Detail 1286 C57BL/6  
polypeptide P30412 UniProt | EBI | MGI Sequence Detail 212 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    104 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013077 eukaryotic-type peptidyl-prolyl cis-trans isomerase C
  • PDB
  • EC
  • InterPro Domains
    IPR029000 Cyclophilin-like domain
    IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase
    IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
    IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Molecular
Reagents
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  • All nucleic 68
    cDNA 68

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13593
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:17287 Friedman J, et al., Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA. Cell. 1991 Aug 23;66(4):799-806
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory