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Prl3d1 Gene Detail
Summary
  • Symbol
    Prl3d1
  • Name
    prolactin family 3, subfamily d, member 1
  • Synonyms
    Csh1, mPL-I, Pl-1, Pl1, placental lactogen 1, PL-Ia, prolactin-like 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:97606
    NCBI Gene: 18775
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:27278173-27284241 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.27 cM
  • Mapping Data
    13 experiments
Strain
Comparison
more
  • SNPs within 2kb
    338 from dbSNP Build 142
  • Strain Annotations
    17
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97606
 protein coding gene Chr13:27278172-27284243 (+)
129S1/SvImJ ENSMUSG00200028586
 protein coding gene Chr13:24437860-24443930 (+)
A/J ENSMUSG00195036185
 protein coding gene Chr13:23576046-23582116 (+)
AKR/J ENSMUSG00220012545
 protein coding gene Chr13:23385586-23391658 (+)
BALB/cJ ENSMUSG00180021249
 protein coding gene Chr13:23881292-23887360 (+)
C3H/HeJ ENSMUSG00175029492
 protein coding gene Chr13:23903963-23910031 (+)
C57BL/6NJ ENSMUSG00215008531
 protein coding gene Chr13:24042949-24049017 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005009411
 protein coding gene Chr13:24066922-24072977 (+)
CBA/J ENSMUSG00210026488
 protein coding gene Chr13:23848242-23854312 (+)
DBA/2J ENSMUSG00185018896
 protein coding gene Chr13:24670170-24676238 (+)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000014584
 protein coding gene Chr13:24322263-24328315 (+)
LP/J ENSMUSG00230018339
 protein coding gene Chr13:33991587-33997655 (+)
NOD/ShiLtJ ENSMUSG00190030880
 protein coding gene Chr13:23652278-23658348 (+)
NZO/HlLtJ ENSMUSG00225044298
 protein coding gene Chr13:27777786-27783854 (+)
PWK/PhJ ENSLUMG00010028856
 protein coding gene Chr13:23168623-23174668 (+)
SPRET/EiJ ENSMSPG00010024011
 protein coding gene Chr13:23098979-23105402 (+)
WSB/EiJ ENSIUOG00005015994
 protein coding gene Chr13:23225158-23231248 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    4
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Prl3d1
  • Incidental Mutations
    Mutagenetix
  • Find Mice (IMSR)
    17 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    876
  • Tissues
    55
  • cDNA Data
    15
  • Literature Summary
    157
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057170 Ensembl Gene Model | MGI Sequence Detail 6069 C57BL/6J ±  kb
transcript ENSMUST00000225330 Ensembl | MGI Sequence Detail 866 Not Applicable  
polypeptide ENSMUSP00000152890 Ensembl | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 20
    Primer pair 13
    Other 19
    Antibodies 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13339, MGD-MRK-13341, MGI:2145212
References
more
  • Summaries
    All 219
    Developmental Gene Expression 157
    Gene Ontology 5
    Phenotypes 16
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:386951 Guertin TM, et al., Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines. Development. 2026 May 15;153(10):dev205276
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory