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Phka2 Gene Detail
Summary
  • Symbol
    Phka2
  • Name
    phosphorylase kinase alpha 2
  • Synonyms
    6330505C01Rik, k, Phk
  • Feature Type
    protein coding gene
  • IDs
    MGI:97577
    NCBI Gene: 110094
  • Gene Overview
    MyGene.info: PHKA2
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:160502166-160598878 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 73.95 cM, cytoband F3-F4
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    320 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97577
protein coding gene ChrX:160501904-160598879 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036231
protein coding gene ChrX:158435237-158531676 (+)
A/J MGP_AJ_G0036201
protein coding gene ChrX:157697686-157782982 (+)
AKR/J MGP_AKRJ_G0036129
protein coding gene ChrX:162693155-162791832 (+)
BALB/cJ MGP_BALBcJ_G0036194
protein coding gene ChrX:155770923-155863429 (+)
C3H/HeJ MGP_C3HHeJ_G0035900
protein coding gene ChrX:158834819-158923714 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036716
protein coding gene ChrX:163149170-163246897 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033538
protein coding gene ChrX:148931033-149012146 (+)
CAST/EiJ MGP_CASTEiJ_G0035189
protein coding gene ChrX:137859340-137942480 (+)
CBA/J MGP_CBAJ_G0035875
protein coding gene ChrX:167792623-167889476 (+)
DBA/2J MGP_DBA2J_G0036041
protein coding gene ChrX:156657797-156751099 (+)
FVB/NJ MGP_FVBNJ_G0035972
protein coding gene ChrX:155774814-155861215 (+)
LP/J MGP_LPJ_G0036126
protein coding gene ChrX:159611869-159707085 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0036004
protein coding gene ChrX:176488785-176596179 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036757
protein coding gene ChrX:157987584-158078731 (+)
PWK/PhJ MGP_PWKPhJ_G0034887
protein coding gene ChrX:134716267-134803293 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034708
protein coding gene ChrX:138260133-138352756 (+)
WSB/EiJ MGP_WSBEiJ_G0035324
protein coding gene ChrX:155936046-156031486 (+)



Homology
more
  • Human Ortholog
    PHKA2, phosphorylase kinase regulatory subunit alpha 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PHKA2, phosphorylase kinase regulatory subunit alpha 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GSD9A, PHK, PYK, PYKL, XLG, XLG2
  • Links
    NCBI Gene ID: 5256
    neXtProt AC: NX_P46019
    UniProt: P46019

  • Chr Location
    Xp22.13; chrX:18892298-18984362 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human PHKA2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031295 Ensembl Gene Model | MGI Sequence Detail 96713 C57BL/6J ±  kb
transcript ENSMUST00000033652 Ensembl | MGI Sequence Detail 4133 Not Applicable  
polypeptide ENSMUSP00000033652 Ensembl | MGI Sequence Detail 1235 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-11547, MGD-MRK-13293, MGD-MRK-13296, MGI:1923403, MGI:97575
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:5367 Huijing F, et al., Location of phosphorylase kinase (Phk) in the mouse X chromosome. Biochem Genet. 1973 Jun;9(2):193-6
  • Latest
    J:229484 Conte D, et al., The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand. Hum Mol Genet. 2016 Feb 15;25(4):740-54

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory