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Pgm3
Gene Detail
Symbol

Name
ID
Pgm3
phosphoglucomutase 3
MGI:97566
Synonyms
2810473H05Rik, GlcNAc-P mutase, Pgm-3
Feature Type
protein coding gene
Genetic Map
Chromosome 9
46.58 cM, cytoband E3.2
Detailed Genetic Map ± 1 cM


Mapping data(24)
Sequence Map
Chr9:86554377-86571842 bp, - strand
From VEGA annotation of GRCm38

  17466 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9205  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phosphoacetylglucosamine mutase
Gene Tree: Pgm3

Human
homologs
Human Homolog PGM3, phosphoglucomutase 3
NCBI Gene ID 5238
neXtProt AC  NX_O95394
Human Synonyms  AGM1, IMD23, PAGM, PGM 3
Human Chr (Location)  6q14.1-q15; chr6:83164873-83193936 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PGM3
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Chemically induced (ENU)(1) Gene trapped(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a hypomorphic allele exhibit male infertility, anemia, leukopenia, thrombocytopenia, abnormal pancreatic and salivary gland morphology, and splenomegaly.
 
Interactions
Pgm3 interacts with 352 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process carbohydrate metabolic process, embryo development, ...
Component cytosol
Function intramolecular transferase activity, phosphotransferases, isomerase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (113)    Tissues (106)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
Northern blot 19
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(19) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000045044 (Evidence)
Ensembl Gene ModelENSMUSG00000056131 (Evidence)
Entrez Gene109785 (Evidence)
NIA Mouse Gene IndexU031159
EC5.4.2.3
PDB1WJW
Consensus CDS ProjectCCDS23381.1, CCDS52877.1
International Mouse Knockout Project StatusPgm3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045044 VEGA Gene Model | MGI Sequence Detail 17466 C57BL/6J ±  kb
transcript OTTMUST00000118375 VEGA | MGI Sequence Detail 2666 Not Applicable 
polypeptide OTTMUSP00000066077 VEGA | MGI Sequence Detail 542 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(4) UniProt(13)
Polymorphisms
SNPs within 2kb(127 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I
InterPro IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II
InterPro IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III
InterPro IPR016066 Alpha-D-phosphohexomutase, conserved site
InterPro IPR005843 Alpha-D-phosphohexomutase, C-terminal
InterPro IPR016657 Phosphoacetylglucosamine mutase
Protein Ontology PR:000012617 phosphoacetylglucosamine mutase
References
(Earliest) J:13849 Chasalow F, et al., Pgm-3. Mouse News Lett. 1980;62:74
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(55)
Other
accession IDs
MGD-MRK-13277, MGD-MRK-13280, MGI:1920033, MGI:2143369, MGI:2143392

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory