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Pgm3
Gene Detail
 Symbol
Name
ID
Pgm3
phosphoglucomutase 3
MGI:97566
Synonyms 2810473H05Rik, GlcNAc-P mutase, Pgm-3
Feature Type protein coding gene
Genetic Map
Chromosome 9
46.58 cM, cytoband E3.2
Detailed Genetic Map ± 1 cM


Mapping data(24)
Sequence Map
Chr9:86552476-86571842 bp, - strand
From NCBI annotation of GRCm38

  19367 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9205  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: phosphoacetylglucosamine mutase
Gene Tree: Pgm3

Human
homologs
Human Homolog PGM3, phosphoglucomutase 3
NCBI Gene ID 5238
neXtProt AC  NX_O95394
Human Synonyms  AGM1, IMD23, PAGM, PGM 3
Human Chr (Location)  6q14.1-q15; chr6:83164873-83193936 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PGM3
Alleles
and
phenotypes
All alleles(8) : Chemically induced (ENU)(1) Gene trapped(7)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a hypomorphic allele exhibit male infertility, anemia, leukopenia, thrombocytopenia, abnormal pancreatic and salivary gland morphology, and splenomegaly.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process carbohydrate metabolic process, embryo development, ...
Component cytosol
Function intramolecular transferase activity, phosphotransferases, isomerase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (113)    Tissues (106)    Images (1)
Theiler Stages: 22, 26, 28
Assay TypeResults
RNA in situ 94
Northern blot 19
cDNA source data(19)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(21) cDNA(19) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000056131 (Evidence)
Entrez Gene109785 (Evidence)
NIA Mouse Gene IndexU031159
EC5.4.2.3
PDB1WJW
Consensus CDS ProjectCCDS23381.1, CCDS52877.1
International Mouse Knockout Project StatusPgm3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 109785 NCBI Gene Model | MGI Sequence Detail 19367 C57BL/6J ±  kb
transcript NM_028352 RefSeq | MGI Sequence Detail 4582 C57BL/6 
polypeptide Q9CYR6 UniProt | EBI | MGI Sequence Detail 542 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(4) UniProt(7)
Polymorphisms SNPs within 2kb(139 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I
InterPro IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II
InterPro IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III
InterPro IPR016066 Alpha-D-phosphohexomutase, conserved site
InterPro IPR005843 Alpha-D-phosphohexomutase, C-terminal
InterPro IPR016657 Phosphoacetylglucosamine mutase
Protein Ontology PR:000012617 phosphoacetylglucosamine mutase
Graphical View of Protein Domain Structure
References (Earliest) J:13849 Chasalow F, et al., Pgm-3. Mouse News Lett. 1980;62:74
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(55)
Other
accession IDs
MGD-MRK-13277, MGD-MRK-13280, MGI:1920033, MGI:2143369, MGI:2143392

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory