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Pgm2 Gene Detail
Summary
  • Symbol
    Pgm2
  • Name
    phosphoglucomutase 2
  • Synonyms
    3230402E02Rik, Pgm1, Pgm-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97564
    NCBI Gene: 66681
  • Gene Overview
    MyGene.info: PGM2
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:64092950-64128351 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 32.80 cM, cytoband C3.3
  • Mapping Data
    84 experiments
Strain
Comparison
more
  • SNPs within 2kb
    183 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97564
protein coding gene Chr5:64092831-64128355 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029565
protein coding gene Chr5:63660433-63699457 (+)
A/J MGP_AJ_G0029533
protein coding gene Chr5:61295035-61327194 (+)
AKR/J MGP_AKRJ_G0029481
protein coding gene Chr5:63210868-63243346 (+)
BALB/cJ MGP_BALBcJ_G0029542
protein coding gene Chr5:61974047-62003363 (+)
C3H/HeJ MGP_C3HHeJ_G0029265
protein coding gene Chr5:63580325-63610948 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029996
protein coding gene Chr5:66305526-66341363 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027236
protein coding gene Chr5:57396250-57425774 (+)
CAST/EiJ MGP_CASTEiJ_G0028673
protein coding gene Chr5:62641706-62678874 (+)
CBA/J MGP_CBAJ_G0029234
protein coding gene Chr5:68413981-68462315 (+)
DBA/2J MGP_DBA2J_G0029380
protein coding gene Chr5:61324305-61356934 (+)
FVB/NJ MGP_FVBNJ_G0029340
protein coding gene Chr5:60501636-60531418 (+)
LP/J MGP_LPJ_G0029465
protein coding gene Chr5:64127974-64161866 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029368
protein coding gene Chr5:71357745-71393317 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030029
protein coding gene Chr5:62903317-62934323 (+)
PWK/PhJ MGP_PWKPhJ_G0028397
protein coding gene Chr5:60295178-60325020 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028231
protein coding gene Chr5:62248325-62280187 (+)
WSB/EiJ MGP_WSBEiJ_G0028754
protein coding gene Chr5:63121264-63153190 (+)



Homology
more
  • Human Ortholog
    PGM2, phosphoglucomutase 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PGM2, phosphoglucomutase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MSTP006
  • Links
    NCBI Gene ID: 55276
    neXtProt AC: NX_Q96G03
    UniProt: Q96G03

  • Chr Location
    4p14; chr4:37826660-37862938 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6693
    1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PGM2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 6 alleles in 3 genetic backgrounds
    24 phenotype references
Four electrophoretic variants are known, each with a 5-band pattern: the a allele in C57BL/6, BALB/c and AKR; b allele in DBA/2 and SJL; c allele in C3H/He; and d allele in 129/Re. Heterozygotes show a mixture of bands. Mice homozygous for a spontaneous null allele or ENU induced alleles are viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029171 Ensembl Gene Model | MGI Sequence Detail 35402 C57BL/6J ±  kb
transcript ENSMUST00000087324 Ensembl | MGI Sequence Detail 2369 Not Applicable  
polypeptide ENSMUSP00000084582 Ensembl | MGI Sequence Detail 620 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000012615 phosphoglucomutase-2
  • EC
  • InterPro Domains
    IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I
    IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II
    IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III
    IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III
    IPR016066 Alpha-D-phosphohexomutase, conserved site
    IPR005843 Alpha-D-phosphohexomutase, C-terminal
    IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily
Molecular
Reagents
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  • All nucleic 48
    cDNA 46
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-13275, MGD-MRK-13278, MGI:1913931
References
more
  • Summaries
    All 121
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 24
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory