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Pgk2
Gene Detail
 Symbol
Name
ID
Pgk2
phosphoglycerate kinase 2
MGI:97563
Synonyms Pgk-2, Tcp-2, Tcp-2
Feature Type protein coding gene
Genetic Map
Chromosome 17
19.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(24)
Sequence Map
Chr17:40207018-40208609 bp, - strand
From NCBI annotation of GRCm38

  1592 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:57138  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: phosphoglycerate kinase
Gene Tree: Pgk2

Human
homologs
Human Homolog PGK2, phosphoglycerate kinase 2
NCBI Gene ID 5232
neXtProt AC  NX_P07205
Human Synonyms  dJ417L20.2, HEL-S-272, PGKB, PGKPS
Human Chr (Location)  6p12.3; chr6:49785651-49787340 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit decreased male fertility associated with reduced sperm motility.
 
Interactions
Pgk2 interacts with 74 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process glycolytic process, phosphorylation, ...
Component cilium, cytoplasm, ...
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (122)    Tissues (106)    Images (2)
Theiler Stages: 14, 18, 21, 22, 23, 25, 26, 27, 28
Assay TypeResults
RNA in situ 94
RT-PCR 28
cDNA source data(33)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(48) Genomic(10) cDNA(33) Primer pair(4) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000031233 (Evidence)
Entrez Gene18663 (Evidence)
UniGene717
DFCITC1580575
DoTSDT.488729
NIA Mouse Gene IndexU260518
EC2.7.2.3
PDB2P9Q, 2P9T, 2PAA
Consensus CDS ProjectCCDS28782.1
International Mouse Knockout Project StatusPgk2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 18663 NCBI Gene Model | MGI Sequence Detail 1592 C57BL/6J ±  kb
transcript NM_031190 RefSeq | MGI Sequence Detail 1592 Not Specified 
polypeptide P09041 UniProt | EBI | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms RFLP(4) : SNPs within 2kb(9 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001576 Phosphoglycerate kinase
InterPro IPR015911 Phosphoglycerate kinase, conserved site
InterPro IPR015901 Phosphoglycerate kinase, C-terminal
InterPro IPR015824 Phosphoglycerate kinase, N-terminal
Protein Ontology PR:000012608 phosphoglycerate kinase 2
Graphical View of Protein Domain Structure
References (Earliest) J:16462 VandeBerg JL, et al., Mammalian testis phosphoglycerate kinase. Nat New Biol. 1973;243:48-50
(Latest) J:193996 Chauvin T, et al., A systematic analysis of a deep mouse epididymal sperm proteome. Biol Reprod. 2012;87(6):141
All references(78)
Other
accession IDs
MGD-MRK-13265, MGD-MRK-13274, MGD-MRK-14818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory