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Pgk1 Gene Detail
Summary
  • Symbol
    Pgk1
  • Name
    phosphoglycerate kinase 1
  • Synonyms
    Pgk-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97555
    NCBI Gene: 18655
  • Gene Overview
    MyGene.info: PGK1
Location & Maps
more
  • Sequence Map
    ChrX:106187100-106203699 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16600 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 47.36 cM, cytoband C-D
  • Mapping Data
    62 experiments
  • Sequence Tags
Homology
more
  • Human Ortholog
    PGK1, phosphoglycerate kinase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PGK1, phosphoglycerate kinase 1
    Orthology source: HomoloGene
  • Synonyms
    HEL-S-68p, MIG10, PGKA
  • Links
    NCBI Gene ID: 5230
    neXtProt AC: NX_P00558

  • Chr Location
    Xq13.3; chrX:78104169-78126827 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human PGK1 associations

Human Disease Mouse Models
       Phosphoglycerate Kinase 1 Deficiency   OMIM: 300653
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype reference
  • All Mutations and Alleles
    1
  • Gene trapped
    1
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018277 VEGA Gene Model | MGI Sequence Detail 16600 C57BL/6J ±  kb
transcript OTTMUST00000044166 VEGA | MGI Sequence Detail 1825 Not Applicable  
polypeptide OTTMUSP00000019855 VEGA | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    63 from dbSNP Build 142
  • PCR
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    Genomic 18
    cDNA 23
    Primer pair 5
    Other 5

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-13258, MGD-MRK-13266
References
more
  • Summaries
    All 143
    Developmental Gene Expression 43
    Gene Ontology 6
    Phenotypes 1
  • Earliest
    J:5427 Kozak LP, et al., X linkage of phosphoglycerate kinase in the mouse. Biochem Genet. 1974 Jan;11(1):41-7
  • Latest
    J:227211 Zhang Y, et al., Maternal bile acid transporter deficiency promotes neonatal demise. Nat Commun. 2015;6:8186

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory