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Pgk1
Gene Detail
 Symbol
Name
ID
Pgk1
phosphoglycerate kinase 1
MGI:97555
STS DXH1, DXMit64
Synonyms Pgk-1
Feature Type protein coding gene
Genetic Map
Chromosome X
47.36 cM, cytoband C-D
Detailed Genetic Map ± 1 cM


Mapping data(62)
Sequence Map
ChrX:106187100-106203699 bp, + strand
From VEGA annotation of GRCm38

  16600 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21542  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phosphoglycerate kinase
Gene Tree: Pgk1

Human
homologs
Human Homolog PGK1, phosphoglycerate kinase 1
NCBI Gene ID 5230
neXtProt AC  NX_P00558
Human Synonyms  HEL-S-68p, MIG10, PGKA
Human Chr (Location)  Xq13.3; chrX:78104169-78126827 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PGK1
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
Incidental mutations (data from APF )
Interactions
Pgk1 interacts with 93 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process carbohydrate metabolic process, gluconeogenesis, ...
Component cytosol, extracellular vesicular exosome, ...
Function ADP binding, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (41 records)
Data Summary: Results (281)    Tissues (142)    Images (44)
Theiler Stages: 21, 22, 23, 26, 28
Assay TypeResults
RNA in situ 255
Northern blot 5
RT-PCR 21
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(51) Genomic(18) cDNA(23) Primer pair(5) Other(5)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000018277 (Evidence)
Ensembl Gene ModelENSMUSG00000062070 (Evidence)
Entrez Gene18655 (Evidence)
DFCITC1573707
DoTSDT.101239040, DT.103571053, DT.110469593, DT.94210531, DT.94210551
NIA Mouse Gene IndexU020126, U044734, U131082, U165094
EC2.7.1.38
Consensus CDS ProjectCCDS30339.1
International Mouse Knockout Project StatusPgk1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018277 VEGA Gene Model | MGI Sequence Detail 16600 C57BL/6J ±  kb
transcript OTTMUST00000044166 VEGA | MGI Sequence Detail 1825 Not Applicable 
polypeptide OTTMUSP00000019855 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(2)
Polymorphisms All PCR and RFLP(8) : PCR(2) RFLP(6) SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000012607 phosphoglycerate kinase 1
References (Earliest) J:5427 Kozak LP, et al., X linkage of phosphoglycerate kinase in the mouse. Biochem Genet. 1974 Jan;11(1):41-7
(Latest) J:194283 Liu J, et al., Sonic hedgehog signaling directly targets Hyaluronic Acid Synthase 2, an essential regulator of phalangeal joint patterning. Dev Biol. 2013 Mar 15;375(2):160-71
All references(148)
Other
accession IDs
MGD-MRK-13258, MGD-MRK-13266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory