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Pgk1
Gene Detail
Symbol

Name
ID
Pgk1
phosphoglycerate kinase 1
MGI:97555
STS
Synonyms
Pgk-1
Feature Type
protein coding gene
Genetic Map
Chromosome X
47.36 cM, cytoband C-D
Detailed Genetic Map ± 1 cM


Mapping data(62)
Sequence Map
ChrX:106187100-106203699 bp, + strand
From VEGA annotation of GRCm38

  16600 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21542  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PGK1
Protein SuperFamily: phosphoglycerate kinase
Gene Tree: Pgk1

Human
homologs
PGK1, phosphoglycerate kinase 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 5230
neXtProt AC: NX_P00558

Human Synonyms: HEL-S-68p, MIG10, PGKA

Human Chr (Location): Xq13.3; chrX:78104169-78126827 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human PGK1

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
Incidental mutations (data from APF )
Interactions
Pgk1 interacts with 92 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process carbohydrate metabolic process, gluconeogenesis, ...
Component cytosol, extracellular exosome, ...
Function ADP binding, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (42 records)
Data Summary: Results (281)    Tissues (142)    Images (44)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 255
Northern blot 5
RT-PCR 21
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA PGK1 ; Xenbase pgk1    NEW 
Molecular
reagents
All nucleic(51) Genomic(18) cDNA(23) Primer pair(5) Other(5)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000018277 (Evidence)
Ensembl Gene Model ENSMUSG00000062070 (Evidence)
Entrez Gene 18655 (Evidence)
DFCI TC1573707
DoTS DT.101239040, DT.103571053, DT.110469593, DT.94210531, DT.94210551
NIA Mouse Gene Index U020126, U044734, U131082, U165094
EC 2.7.1.38
Consensus CDS Project CCDS30339.1
International Mouse Phenotyping Consortium Status Pgk1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018277 VEGA Gene Model | MGI Sequence Detail 16600 C57BL/6J ±  kb
transcript OTTMUST00000044166 VEGA | MGI Sequence Detail 1825 Not Applicable 
polypeptide OTTMUSP00000019855 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(2)
Polymorphisms
All PCR and RFLP(8) : PCR(2) RFLP(6) SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000012607 phosphoglycerate kinase 1
References
(Earliest) J:5427 Kozak LP, et al., X linkage of phosphoglycerate kinase in the mouse. Biochem Genet. 1974 Jan;11(1):41-7
(Latest) J:204566 Gendrel AV, et al., Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
All references(145)
Other
accession IDs
MGD-MRK-13258, MGD-MRK-13266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory