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Cdk18 Gene Detail
Summary
  • Symbol
    Cdk18
  • Name
    cyclin-dependent kinase 18
  • Synonyms
    Pctk3
  • Feature Type
    protein coding gene
  • IDs
    MGI:97518
    NCBI Gene: 18557
  • Gene Overview
    MyGene.info: CDK18
Location & Maps
more
  • Sequence Map
    Chr1:132112237-132139684 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      27448 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 57.24 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CDK18, cyclin-dependent kinase 18
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDK18, cyclin-dependent kinase 18
    Orthology source: HomoloGene
  • Synonyms
    PCTAIRE, PCTAIRE3, PCTK3
  • Links
    NCBI Gene ID: 5129
    neXtProt AC: NX_Q07002

  • Chr Location
    1q31-q32; chr1:205504556-205532793 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    2
  • Gene trapped
    7
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    3 involving Cdk18
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049382 VEGA Gene Model | MGI Sequence Detail 27448 C57BL/6J ±  kb
transcript OTTMUST00000125871 VEGA | MGI Sequence Detail 4355 Not Applicable  
polypeptide OTTMUSP00000068123 VEGA | MGI Sequence Detail 451 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    220 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    cDNA 28

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13198, MGI:2138128
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:3108 Okuda T, et al., PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene. 1992 Nov;7(11):2249-58
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory