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Cdk18
Gene Detail
 Symbol
Name
ID
Cdk18
cyclin-dependent kinase 18
MGI:97518
Synonyms Pctk3
Feature Type protein coding gene
Genetic Map
Chromosome 1
57.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:132113550-132139685 bp, - strand
From Ensembl annotation of GRCm38

  26136 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1949  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Cdk18

Human
homologs
Human Homolog CDK18, cyclin-dependent kinase 18
NCBI Gene ID 5129
neXtProt AC  NX_Q07002
Human Synonyms  PCTAIRE, PCTAIRE3, PCTK3
Human Chr (Location)  1q31-q32; chr1:205504556-205532793 (+)  GRCh38
Alleles
and
phenotypes
All alleles(10) : Targeted(3) Gene trapped(7)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process phosphorylation, protein phosphorylation
Function ATP binding, cyclin-dependent protein serine/threonine kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (15)    Tissues (15)   
Theiler Stages: 26, 28
Assay TypeResults
Northern blot 15
cDNA source data(28)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(28) cDNA(28)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000026437 (Evidence)
Entrez Gene18557 (Evidence)
UniGene28130
DFCITC1582028, TC1739287
DoTSDT.110898934, DT.525941
NIA Mouse Gene IndexU021758
EC2.7.11.22
Consensus CDS ProjectCCDS15281.1
International Mouse Knockout Project StatusCdk18
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026437 Ensembl Gene Model | MGI Sequence Detail 26136 C57BL/6J ±  kb
transcript ENSMUST00000112362 Ensembl | MGI Sequence Detail 1705 Not Applicable 
polypeptide ENSMUSP00000107981 Ensembl | MGI Sequence Detail 451 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(3) UniProt(3)
Polymorphisms SNPs within 2kb(215 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000012443 cyclin-dependent kinase 18
References (Earliest) J:3108 Okuda T, et al., PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene. 1992 Nov;7(11):2249-58
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(33)
Other
accession IDs
MGD-MRK-13198, MGI:2138128

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory