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Cdk17
Gene Detail
 Symbol
Name
ID
Cdk17
cyclin-dependent kinase 17
MGI:97517
Synonyms 6430598J10Rik, MGC:25109, Pctk2
Feature Type protein coding gene
Genetic Map
Chromosome 10
47.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:93160876-93241342 bp, + strand
From NCBI annotation of GRCm38

  80467 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55666  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Cdk17

Human
homologs
Human Homolog CDK17, cyclin-dependent kinase 17
NCBI Gene ID 5128
neXtProt AC  NX_Q00537
Human Synonyms  PCTAIRE2, PCTK2
Human Chr (Location)  12q23.1; chr12:96278261-96400588 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(227) : Gene trapped(223) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cdk17 interacts with 347 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process phosphorylation, protein phosphorylation
Function ATP binding, cyclin-dependent protein serine/threonine kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (32)    Tissues (32)    Images (9)
Theiler Stages: 17, 19, 21, 23, 28
Assay TypeResults
RNA in situ 30
RT-PCR 2
cDNA source data(57)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(59) cDNA(57) Primer pair(1) Other(1)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000020015 (Evidence)
Entrez Gene237459 (Evidence)
UniGene217404
DFCITC1580616, TC1613107, TC1626366, TC1630388, TC1706477
DoTSDT.110620781, DT.528632, DT.91384504, DT.94135048
NIA Mouse Gene IndexU011895, U332799
EC2.7.11.22
Consensus CDS ProjectCCDS48670.1
International Mouse Knockout Project StatusCdk17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 237459 NCBI Gene Model | MGI Sequence Detail 80467 C57BL/6J ±  kb
transcript NM_146239 RefSeq | MGI Sequence Detail 3643 C57BL/6 
polypeptide Q8K0D0 UniProt | EBI | MGI Sequence Detail 523 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(9) UniProt(4)
Polymorphisms SNPs within 2kb(877 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000012442 cyclin-dependent kinase 17
Graphical View of Protein Domain Structure
References (Earliest) J:3108 Okuda T, et al., PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene. 1992 Nov;7(11):2249-58
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGD-MRK-13197, MGI:1923461

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory