Cdk17
Gene Detail

Symbol Name ID

Cdk17 cyclin-dependent kinase 17 MGI:97517

Synonyms

6430598J10Rik, MGC:25109, Pctk2

Feature Type

protein coding gene

Genetic Map

Chromosome 10

47.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr10:93160876-93241342 bp, + strand From NCBI annotation of GRCm38   80467 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:55666  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Cdk17

Human homologs

Human Homolog		CDK17, cyclin-dependent kinase 17
NCBI Gene ID		5128
neXtProt AC		NX_Q00537
Human Synonyms		PCTAIRE2, PCTK2
Human Chr (Location)		12q23.1; chr12:96672039-96794366 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(224) : Targeted(1) Gene trapped(223)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	phosphorylation, protein phosphorylation
Function	ATP binding, cyclin-dependent protein serine/threonine kinase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (32)    Tissues (32)    Images (9)
Theiler Stages: 17, 19, 21, 23, 28

Assay Type	Results
RNA in situ	30
RT-PCR	2

cDNA source data(54)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(56) cDNA(54) Primer pair(1) Other(1)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000020015 (Evidence)
Entrez Gene	237459 (Evidence)
UniGene	217404
DFCI	TC1580616, TC1613107, TC1626366, TC1630388, TC1706477
DoTS	DT.110620781, DT.528632, DT.91384504, DT.94135048
NIA Mouse Gene Index	U011895, U332799
EC	2.7.11.22
Consensus CDS Project	CCDS48670.1
International Mouse Knockout Project Status	Cdk17

Sequences

Length	Strain/Species
genomic	237459	NCBI Gene Model | MGI Sequence Detail	80467	C57BL/6J
transcript	NM_146239	RefSeq | MGI Sequence Detail	3643	C57BL/6
polypeptide	Q8K0D0	UniProt | EBI | MGI Sequence Detail	523	Not Applicable

All sequences(39) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(368 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017441	Protein kinase, ATP binding site
InterPro	IPR000719	Protein kinase, catalytic domain
InterPro	IPR011009	Protein kinase-like domain
InterPro	IPR002290	Serine/threonine- / dual-specificity protein kinase, catalytic domain
InterPro	IPR008271	Serine/threonine-protein kinase, active site
Protein Ontology	PR:000012442	serine/threonine-protein kinase PCTAIRE-2

Graphical View of Protein Domain Structure

References

(Earliest) J:3108 Okuda T, et al., PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene. 1992 Nov;7(11):2249-58
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Other accession IDs

MGD-MRK-13197, MGI:1923461