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Orm1 Gene Detail
Summary
  • Symbol
    Orm1
  • Name
    orosomucoid 1
  • Synonyms
    Agp-1, Agp-2, Orm-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97443
    NCBI Gene: 18405
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:63344560-63348163 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 33.96 cM
  • Mapping Data
    23 experiments
  • Sequence Tags
Strain
Comparison
more
  • SNPs within 2kb
    57 from dbSNP Build 142
  • Strain Annotations
    16
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97443
protein coding gene Chr4:63344556-63348163 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028364
protein coding gene Chr4:62354928-62358558 (+)
A/J MGP_AJ_G0028325
protein coding gene Chr4:60103353-60106956 (+)
AKR/J MGP_AKRJ_G0028274
protein coding gene Chr4:61743167-61746771 (+)
BALB/cJ MGP_BALBcJ_G0028345
protein coding gene Chr4:60293922-60297525 (+)
C3H/HeJ MGP_C3HHeJ_G0028063
protein coding gene Chr4:62269203-62272806 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028785
protein coding gene Chr4:64486865-64491947 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027499
protein coding gene Chr4:60237300-60240924 (+)
CBA/J MGP_CBAJ_G0028030
protein coding gene Chr4:66739083-66744794 (+)
DBA/2J MGP_DBA2J_G0028180
protein coding gene Chr4:59957524-59961127 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0028277
protein coding gene Chr4:62623140-62626744 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028172
protein coding gene Chr4:69839147-69843871 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028821
protein coding gene Chr4:61860863-61864493 (+)
PWK/PhJ MGP_PWKPhJ_G0027226
protein coding gene Chr4:58469771-58478773 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027055
protein coding gene Chr4:59311329-59313256 (+)
WSB/EiJ MGP_WSBEiJ_G0027579
protein coding gene Chr4:61859384-61864471 (+)



Homology
more
  • Human Ortholog
    ORM2, orosomucoid 2
  • Vertebrate Orthologs
    3
  • Human Ortholog
    ORM2, orosomucoid 2
    Orthology source: HGNC
  • Synonyms
    AGP2, AGP-B, AGP-B'
  • Links
    NCBI Gene ID: 5005
    neXtProt AC: NX_P19652
    UniProt: P19652

  • Chr Location
    9q32; chr9:114329789-114333256 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039196 Ensembl Gene Model | MGI Sequence Detail 3604 C57BL/6J ±  kb
transcript ENSMUST00000030044 Ensembl | MGI Sequence Detail 775 Not Applicable  
polypeptide ENSMUSP00000030044 Ensembl | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001500 Alpha-1-acid glycoprotein
    IPR012674 Calycin
    IPR000566 Lipocalin/cytosolic fatty-acid binding domain
Molecular
Reagents
less
  • All nucleic 78
    Genomic 2
    cDNA 73
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-13048, MGD-MRK-13051
References
more
  • Summaries
    All 58
    Developmental Gene Expression 2
    Gene Ontology 3
  • Earliest
    J:6919 Baumann H, et al., Dexamethasone regulation of alpha 1-acid glycoprotein and other acute phase reactants in rat liver and hepatoma cells. J Biol Chem. 1983 Jan 10;258(1):563-70
  • Latest
    J:203296 Porez G, et al., The hepatic orosomucoid/alpha1-acid glycoprotein gene cluster is regulated by the nuclear bile acid receptor FXR. Endocrinology. 2013 Oct;154(10):3690-701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory