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Oas1g
Gene Detail
Symbol

Name
ID
Oas1g
2'-5' oligoadenylate synthetase 1G
MGI:97429
Synonyms
L2, Mmu-L, Mmu-L2, Oas1a, Oias1, Oias-1
Feature Type
protein coding gene
Genetic Map
Chromosome 5
60.65 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:120876142-120887613 bp, - strand
From VEGA annotation of GRCm38

  11472 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1903  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 3 cattle; 1 dog

HCOP human homology predictions: OAS1
Protein SuperFamily: oligo(A) synthetase
Gene Tree: Oas1g

Human
homologs
OAS1, 2'-5'-oligoadenylate synthetase 1, 40/46kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4938
neXtProt AC: NX_P00973

Human Synonyms: IFI-4, OIAS, OIASI

Human Chr (Location): 12q24.2; chr12:112906934-112932049 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human OAS1

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Oas1g interacts with 163 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Component cytoplasm, nucleus
Function 2'-5'-oligoadenylate synthetase activity, double-stranded RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (88)    Tissues (13)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 23
Western blot 14
RT-PCR 51
cDNA source data(29)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(36) Genomic(4) cDNA(30) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000030607 (Evidence)
Ensembl Gene Model ENSMUSG00000066861 (Evidence)
Entrez Gene 23960 (Evidence)
UniGene 389688
Consensus CDS Project CCDS39245.1
International Mouse Phenotyping Consortium Status Oas1g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030607 VEGA Gene Model | MGI Sequence Detail 11472 C57BL/6J ±  kb
transcript OTTMUST00000075803 VEGA | MGI Sequence Detail 1977 Not Applicable 
polypeptide OTTMUSP00000039802 VEGA | MGI Sequence Detail 367 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(3)
Polymorphisms
SNPs within 2kb(7 from dbSNP Build 137)    SNPs within 2kb including multiple locations(13)
References
(Earliest) J:9307 Cohen B, et al., Enhancer-like interferon responsive sequences of the human and murine (2'-5') oligoadenylate synthetase gene promoters. EMBO J. 1988 May;7(5):1411-9
(Latest) J:192649 Kristiansen H, et al., The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. J Interferon Cytokine Res. 2011 Jan;31(1):41-7
All references(34)
Other
accession IDs
MGD-MRK-13023, MGD-MRK-13025, MGI:2140890

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory