Oas1g
Gene Detail

Symbol Name ID

Oas1g 2'-5' oligoadenylate synthetase 1G MGI:97429

Synonyms

L2, Mmu-L, Mmu-L2, Oas1a, Oias1, Oias-1

Feature Type

protein coding gene

Genetic Map

Chromosome 5

60.65 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr5:120876142-120887613 bp, - strand From VEGA annotation of GRCm38   11472 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:1903  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: oligo(A) synthetase
Gene Tree: Oas1g

Human homologs

Human Homolog		OAS1, 2'-5'-oligoadenylate synthetase 1, 40/46kDa
NCBI Gene ID		4938
neXtProt AC		NX_P00973
Human Synonyms		IFI-4, OIAS, OIASI
Human Chr (Location)		12q24.2; chr12:113344739-113357712 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human OAS1

Alleles and phenotypes

All alleles(5) : Targeted(5)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Component	cytoplasm, nucleus
Function	2'-5'-oligoadenylate synthetase activity, double-stranded RNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (88)    Tissues (12)    Images (1)
Theiler Stages: 22, 26, 28

Assay Type	Results
Northern blot	23
Western blot	14
RT-PCR	51

cDNA source data(29)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(36) Genomic(4) cDNA(30) Primer pair(1) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000030607 (Evidence)
Ensembl Gene Model	ENSMUSG00000066861 (Evidence)
Entrez Gene	23960 (Evidence)
UniGene	389688
Consensus CDS Project	CCDS39245.1
International Mouse Knockout Project Status	Oas1g

Sequences

Length	Strain/Species
genomic	OTTMUSG00000030607	VEGA Gene Model | MGI Sequence Detail	11472	C57BL/6J
transcript	OTTMUST00000075803	VEGA | MGI Sequence Detail	1977	Not Applicable
polypeptide	OTTMUSP00000039802	VEGA | MGI Sequence Detail	367	Not Applicable

All sequences(20) RefSeq(2)

Polymorphisms

SNPs(3 from dbSNP Build 128)

References

(Earliest) J:34026 Ichii Y, et al., Mouse 2-5A synthetase cDNA: nucleotide sequence and comparison to human 2-5A synthetase. Nucleic Acids Res. 1986 Dec 22;14(24):10117
(Latest) J:192649 Kristiansen H, et al., The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. J Interferon Cytokine Res. 2011 Jan;31(1):41-7
All references(32)

Other accession IDs

MGD-MRK-13023, MGD-MRK-13025, MGI:2140890