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Odf1
Gene Detail
Symbol

Name
ID
Odf1
outer dense fiber of sperm tails 1
MGI:97424
Feature Type
protein coding gene
Genetic Map
Chromosome 15
15.14 cM, cytoband B2-C
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:38219203-38226735 bp, + strand
From VEGA annotation of GRCm38

  7533 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7456  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: ODF1
Gene Tree: Odf1

Human
homologs
ODF1, outer dense fiber of sperm tails 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4956
neXtProt AC: NX_Q14990

Human Synonyms: CT133, HSPB10, ODF, ODF2, ODF27, ODFP, ODFPG, ODFPGA, ODFPGB, RT7, SODF

Human Chr (Location): 8q22.3; chr8:102551620-102561017 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(36) : Gene trapped(33) Targeted(3)
 
Mice homozygous for a knock-out allele exhibit male infertility associated with asthenozoospermia, oligozoospermia, detached sperm head and absent acrosome reaction. Mice heterozygous for this allele exhibit asthenozoospermia without altered fertility.
 
Interactions
Odf1 interacts with 31 markers (Mir22, Mir27b, Mir141, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process cell differentiation, multicellular organismal development, ...
Component nucleus, outer dense fiber
Function protein domain specific binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (3)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 3
cDNA source data(48)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(52) Genomic(2) cDNA(48) Primer pair(1) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000029159 (Evidence)
Ensembl Gene Model ENSMUSG00000061923 (Evidence)
Entrez Gene 18285 (Evidence)
UniGene 252830
DFCI TC1582148, TC1697264, TC1716523, TC1750055
DoTS DT.494634, DT.55192114
NIA Mouse Gene Index U016188
Consensus CDS Project CCDS49596.1
International Mouse Phenotyping Consortium Status Odf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029159 VEGA Gene Model | MGI Sequence Detail 7533 C57BL/6J ±  kb
transcript OTTMUST00000072319 VEGA | MGI Sequence Detail 1105 Not Applicable 
polypeptide OTTMUSP00000037196 VEGA | MGI Sequence Detail 248 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(48 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002068 Alpha crystallin/Hsp20 domain
InterPro IPR008978 HSP20-like chaperone
Protein Ontology PR:000011597 outer dense fiber protein 1
References
(Earliest) J:26741 Hoyer-Fender S, et al., Sequence of mouse Odf1 cDNA and its chromosomal localization: extension of the linkage group between human chromosome 8 and mouse chromosome 15. Cytogenet Cell Genet. 1995;70(3-4):200-4
(Latest) J:218717 Yang K, et al., Haplo-deficiency of ODF1/HSPB10 in mouse sperm causes relaxation of head-to-tail linkage. Reproduction. 2014 Nov;148(5):499-506
All references(32)
Other
accession IDs
MGD-MRK-13016

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory