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Nfyb Gene Detail
Summary
  • Symbol
    Nfyb
  • Name
    nuclear transcription factor-Y beta
  • Synonyms
    Cbf-A
  • Feature Type
    protein coding gene
  • IDs
    MGI:97317
    NCBI Gene: 18045
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:82584535-82599978 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 40.25 cM, cytoband C3-D1
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    397 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97317
 protein coding gene Chr10:82584534-82599985 (-)
129S1/SvImJ ENSMUSG00200046147
 protein coding gene Chr10:79066897-79082348 (-)
A/J ENSMUSG00195046090
 protein coding gene Chr10:79508773-79524226 (-)
AKR/J ENSMUSG00220039221
 protein coding gene Chr10:79118294-79133746 (-)
BALB/cJ ENSMUSG00180050308
 protein coding gene Chr10:79519168-79534619 (-)
C3H/HeJ ENSMUSG00175045600
 protein coding gene Chr10:79389940-79405391 (-)
C57BL/6NJ ENSMUSG00215051384
 protein coding gene Chr10:79070888-79086333 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015665
 protein coding gene Chr10:76424174-76439885 (-)
CAST/EiJ ENSTCUG00005046810
 protein coding gene Chr10:78891795-78907212 (-)
CBA/J ENSMUSG00210047967
 protein coding gene Chr10:79245929-79261380 (-)
DBA/2J ENSMUSG00185050737
 protein coding gene Chr10:79455469-79470917 (-)
FVB/NJ ENSMUSG00205035478
 protein coding gene Chr10:79172941-79188392 (-)
JF1/MsJ ENSUMUG00000046552
 protein coding gene Chr10:80845464-80860870 (-)
LP/J ENSMUSG00230015303
 protein coding gene Chr10:81357924-81373375 (-)
NOD/ShiLtJ ENSMUSG00190048593
 protein coding gene Chr10:79501965-79517416 (-)
NZO/HlLtJ ENSMUSG00225051429
 protein coding gene Chr10:85644387-85659833 (-)
PWK/PhJ ENSLUMG00010040804
 protein coding gene Chr10:79161207-79176604 (-)
SPRET/EiJ ENSMSPG00010046822
 protein coding gene Chr10:80651708-80667151 (-)
WSB/EiJ ENSIUOG00005049226
 protein coding gene Chr10:79209787-79225232 (-)



Homology
more
  • Human Ortholog
    NFYB, nuclear transcription factor Y subunit beta
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NFYB, nuclear transcription factor Y subunit beta
  • Synonyms
    CBF-A, CBF-B, HAP3, NF-YB
  • Links
    NCBI Gene ID: 4801
    UniProt: P25208

  • Chr Location
    12q23.3; chr12:104117080-104138241 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    51
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    771
  • Tissues
    167
  • cDNA Data
    80
  • Literature Summary
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020248 Ensembl Gene Model | MGI Sequence Detail 15444 C57BL/6J ±  kb
transcript ENSMUST00000130911 Ensembl | MGI Sequence Detail 2554 Not Applicable  
polypeptide ENSMUSP00000122403 Ensembl | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 85
    Genomic 1
    cDNA 80
    Primer pair 4

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-12836, MGI:2143515
References
more
  • Summaries
    All 80
    Developmental Gene Expression 11
    Gene Ontology 14
    Phenotypes 15
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:254595 Yang R, et al., Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis. Immunity. 2015 Aug 18;43(2):251-63
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory