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Nfyb
Gene Detail
Symbol

Name
ID
Nfyb
nuclear transcription factor-Y beta
MGI:97317
Synonyms
Cbf-A
Feature Type
protein coding gene
Genetic Map
Chromosome 10
40.25 cM, cytoband C3-D1
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr10:82748701-82764144 bp, - strand
From VEGA annotation of GRCm38

  15444 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38149  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: transcription factor HAP3
Gene Tree: Nfyb

Human
homologs
Human Homolog NFYB, nuclear transcription factor Y, beta
NCBI Gene ID 4801
neXtProt AC  NX_P25208
Human Synonyms  CBF-A, CBF-B, HAP3, NF-YB
Human Chr (Location)  12q22-q23; chr12:104117080-104138262 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(49) : Gene trapped(47) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Nfyb interacts with 303 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (8 records)
Data Summary: Results (157)    Tissues (156)    Images (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 149
RT-PCR 8
cDNA source data(79)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(81) Genomic(1) cDNA(79) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000032747 (Evidence)
Ensembl Gene ModelENSMUSG00000020248 (Evidence)
Entrez Gene18045 (Evidence)
UniGene245998
DFCITC1576773, TC1722049
DoTSDT.103560601, DT.530871, DT.97359644
NIA Mouse Gene IndexU032063
Consensus CDS ProjectCCDS48654.1
International Mouse Knockout Project StatusNfyb
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032747 VEGA Gene Model | MGI Sequence Detail 15444 C57BL/6J ±  kb
transcript OTTMUST00000081491 VEGA | MGI Sequence Detail 2554 Not Applicable 
polypeptide OTTMUSP00000043614 VEGA | MGI Sequence Detail 207 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(6) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(92 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009072 Histone-fold
InterPro IPR003958 Transcription factor CBF/NF-Y/archaeal histone
InterPro IPR003956 Transcription factor, NFYB/HAP3, conserved site
Protein Ontology PR:000011189 nuclear transcription factor Y subunit beta
References
(Earliest) J:10763 van Huijsduijnen RH, et al., Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits. EMBO J. 1990 Oct;9(10):3119-27
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(63)
Other
accession IDs
MGD-MRK-12836, MGI:2143515

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory