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Sept2 Gene Detail
Summary
  • Symbol
    Sept2
  • Name
    septin 2
  • Synonyms
    mKIAA0158, Nedd5
  • Feature Type
    protein coding gene
  • IDs
    MGI:97298
    NCBI Gene: 18000
  • Gene Overview
    MyGene.info: SEPTIN2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:93478968-93509733 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 47.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97298
protein coding gene Chr1:93478964-93510260 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016343
protein coding gene Chr1:95104869-95137109 (+)
A/J MGP_AJ_G0016324
protein coding gene Chr1:91697044-91726797 (+)
AKR/J MGP_AKRJ_G0016285
protein coding gene Chr1:94407611-94437808 (+)
BALB/cJ MGP_BALBcJ_G0016280
protein coding gene Chr1:91881094-91912729 (+)
C3H/HeJ MGP_C3HHeJ_G0016109
protein coding gene Chr1:94660835-94691528 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016739
protein coding gene Chr1:98719909-98752103 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014457
protein coding gene Chr1:85952381-85984167 (+)
CAST/EiJ MGP_CASTEiJ_G0015692
protein coding gene Chr1:93991555-94023022 (+)
CBA/J MGP_CBAJ_G0016083
protein coding gene Chr1:101912762-101947924 (+)
DBA/2J MGP_DBA2J_G0016188
protein coding gene Chr1:90893416-90923632 (+)
FVB/NJ MGP_FVBNJ_G0016187
protein coding gene Chr1:89969264-90000037 (+)
LP/J MGP_LPJ_G0016259
protein coding gene Chr1:96284005-96315662 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016212
protein coding gene Chr1:105019404-105053381 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016778
protein coding gene Chr1:94421955-94454287 (+)
PWK/PhJ MGP_PWKPhJ_G0015477
protein coding gene Chr1:90332924-90363409 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015261
protein coding gene Chr1:93370345-93406366 (+)
WSB/EiJ MGP_WSBEiJ_G0015752
protein coding gene Chr1:94240983-94274194 (+)



Homology
more
  • Human Ortholog
    SEPTIN2, septin 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEPTIN2, septin 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DIFF6, hNedd5, NEDD5, NEDD-5, Pnutl3, SEPT2
  • Links
    NCBI Gene ID: 4735
    neXtProt AC: NX_Q15019
    UniProt: Q15019

  • Chr Location
    2q37.3; chr2:241315187-241354027 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3243
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SEPTIN2
  • Protein SuperFamily
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 18000 NCBI Gene Model | MGI Sequence Detail 30766 C57BL/6J ±  kb
transcript NM_001159719 RefSeq | MGI Sequence Detail 3267 Not Specified  
polypeptide P42208 UniProt | EBI | MGI Sequence Detail 361 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 250
    cDNA 248
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-12811, MGI:2138573
References
more
  • Summaries
    All 56
    Developmental Gene Expression 8
    Gene Ontology 14
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:208280 Bai X, et al., Novel septin 9 repeat motifs altered in neuralgic amyotrophy bind and bundle microtubules. J Cell Biol. 2013 Dec 23;203(6):895-905

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory