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Nedd1 Gene Detail
Summary
  • Symbol
    Nedd1
  • Name
    neural precursor cell expressed, developmentally down-regulated gene 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97293
    NCBI Gene: 17997
  • Gene Overview
    MyGene.info: NEDD1
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:92684745-92722418 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 47.25 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    489 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97293
protein coding gene Chr10:92684745-92722420 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017646
protein coding gene Chr10:94054732-94092467 (-)
A/J MGP_AJ_G0017625
protein coding gene Chr10:90800442-90838183 (-)
AKR/J MGP_AKRJ_G0017583
protein coding gene Chr10:93387596-93425331 (-)
BALB/cJ MGP_BALBcJ_G0017588
protein coding gene Chr10:91068821-91106758 (-)
C3H/HeJ MGP_C3HHeJ_G0017411
protein coding gene Chr10:93397044-93434633 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018045
protein coding gene Chr10:97148331-97186911 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015727
protein coding gene Chr10:86430246-86470219 (-)
CAST/EiJ MGP_CASTEiJ_G0016976
protein coding gene Chr10:93349263-93389622 (-)
CBA/J MGP_CBAJ_G0017380
protein coding gene Chr10:101177278-101219927 (-)
DBA/2J MGP_DBA2J_G0017486
protein coding gene Chr10:89897761-89935554 (-)
FVB/NJ MGP_FVBNJ_G0017478
protein coding gene Chr10:89123100-89160872 (-)
LP/J MGP_LPJ_G0017560
protein coding gene Chr10:94669058-94707203 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017509
protein coding gene Chr10:102541241-102581444 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018082
protein coding gene Chr10:93291361-93329827 (-)
PWK/PhJ MGP_PWKPhJ_G0016757
protein coding gene Chr10:89968961-90007391 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016545
protein coding gene Chr10:92085087-92124665 (-)
WSB/EiJ MGP_WSBEiJ_G0017035
protein coding gene Chr10:93255414-93294054 (-)



Homology
more
  • Human Ortholog
    NEDD1, NEDD1 gamma-tubulin ring complex targeting factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NEDD1, NEDD1 gamma-tubulin ring complex targeting factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GCP-WD, TUBGCP7
  • Links
    NCBI Gene ID: 121441
    neXtProt AC: NX_Q8NHV4
    UniProt: Q8NHV4

  • Chr Location
    12q23.1; chr12:96907222-96953691 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7439
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NEDD1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 17997 NCBI Gene Model | MGI Sequence Detail 37674 C57BL/6J ±  kb
    transcript NM_008682 RefSeq | MGI Sequence Detail 3542 C57BL/6  
    polypeptide P33215 UniProt | EBI | MGI Sequence Detail 660 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 104
      cDNA 104

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-12806
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 9
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:236802 Muroyama A, et al., Divergent regulation of functionally distinct gamma-tubulin complexes during differentiation. J Cell Biol. 2016 Jun 20;213(6):679-92

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    last database update
    11/10/2020
    MGI 6.16
    The Jackson Laboratory