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Ncam2 Gene Detail
Summary
  • Symbol
    Ncam2
  • Name
    neural cell adhesion molecule 2
  • Synonyms
    Ncam-2, Ocam, R4B12 antigen, RNCAM
  • Feature Type
    protein coding gene
  • IDs
    MGI:97282
    NCBI Gene: 17968
Location & Maps
more
  • Sequence Map
    Chr16:81200697-81624285 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      423589 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 45.89 cM, cytoband C1-3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    NCAM2, neural cell adhesion molecule 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    NCAM2, neural cell adhesion molecule 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    NCAM21
  • Links
    NCBI Gene ID: 4685
    neXtProt AC: NX_O15394

  • Chr Location
    21q21.1; chr21:20998315-21540630 (+)  GRCh38.p2

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    18
  • Gene trapped
    8
  • Targeted
    10
  • Genomic Mutations
    4 involving Ncam2
  • Incidental Mutations
A gene trap insertion into an intron of this gene results in no obvious phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014960 VEGA Gene Model | MGI Sequence Detail 423589 C57BL/6J ±  kb
transcript OTTMUST00000035517 VEGA | MGI Sequence Detail 3563 Not Applicable  
polypeptide OTTMUSP00000015902 VEGA | MGI Sequence Detail 837 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1150 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 1
    cDNA 21
    Primer pair 3

    Microarray probesets 6
Other
Accession IDs
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MGD-MRK-12787, MGD-MRK-12788, MGI:1095738
References
more
  • Summaries
    All 56
    Developmental Gene Expression 23
    Diseases 1
    Gene Ontology 3
    Phenotypes 15
  • Earliest
    J:41769 Yoshihara Y, et al., OCAM: A new member of the neural cell adhesion molecule family related to zone-to-zone projection of olfactory and vomeronasal axons. J Neurosci. 1997 Aug 1;17(15):5830-42
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory