Ncam2
Gene Detail

Symbol

Name
ID

Ncam2
neural cell adhesion molecule 2
MGI:97282

Synonyms

Ncam-2, Ocam, R4B12 antigen, RNCAM

Feature Type

protein coding gene

Genetic Map

Chromosome 16
45.89 cM, cytoband C1-3
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr16:81200697-81624285 bp, + strand From VEGA annotation of GRCm38   423589 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:3336  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: cell adhesion molecule, NCAM/Fasciclin-2 types
Gene Tree: Ncam2

Human
homologs

Human Homolog		NCAM2, neural cell adhesion molecule 2
NCBI Gene ID		4685
neXtProt AC		NX_O15394
Human Synonyms		NCAM21
Human Chr (Location)		21q21.1; chr21:20998315-21541571 (+)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(16) : Gene trapped(8) Targeted(8)
Genomic Mutations involving Ncam2 (2)
Incidental mutations (data from Mutagenetix , APF )
 

A gene trap insertion into an intron of this gene results in no obvious phenotype.

 

Interactions

Ncam2 interacts with 304 markers (Mir1a-1, Mir1a-2, Mir1b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (8 annotations)

Process	cell adhesion
Component	anchored component of membrane, axon, ...

External Resources: FuncBase

Expression

Literature Summary: (22 records)

Data Summary: Results (212)    Tissues (133)    Images (22)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	194
RT-PCR	18

cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(25) Genomic(1) cDNA(21) Primer pair(3)
Microarray probesets(6)

Other database
links

VEGA Gene Model	OTTMUSG00000014960 (Evidence)
Ensembl Gene Model	ENSMUSG00000022762 (Evidence)
Entrez Gene	17968 (Evidence)
UniGene	433941
DFCI	TC1585618, TC1590900
DoTS	DT.55270383, DT.87050236, DT.94137365
NIA Mouse Gene Index	U017313
Consensus CDS Project	CCDS28281.1, CCDS49888.1
International Mouse Knockout Project Status	Ncam2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014960	VEGA Gene Model | MGI Sequence Detail	423589	C57BL/6J
transcript	OTTMUST00000035517	VEGA | MGI Sequence Detail	3563	Not Applicable
polypeptide	OTTMUSP00000015902	VEGA | MGI Sequence Detail	837	Not Applicable

All sequences(35) RefSeq(4) UniProt(3)

Polymorphisms

SNPs within 2kb(1155 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR003961	Fibronectin, type III
InterPro	IPR013098	Immunoglobulin I-set
InterPro	IPR007110	Immunoglobulin-like domain
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003598	Immunoglobulin subtype 2
InterPro	IPR009138	Neural cell adhesion
Protein Ontology	PR:000011018	neural cell adhesion molecule 2

References

(Earliest) J:41769 Yoshihara Y, et al., OCAM: A new member of the neural cell adhesion molecule family related to zone-to-zone projection of olfactory and vomeronasal axons. J Neurosci. 1997 Aug 1;17(15):5830-42
(Latest) J:208419 Basta JM, et al., Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58
All references(60)

Other
accession IDs

MGD-MRK-12787, MGD-MRK-12788, MGI:1095738