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Myog
Gene Detail
 Symbol
Name
ID
Myog
myogenin
MGI:97276
Synonyms bHLHc3, myo
Feature Type protein coding gene
Genetic Map
Chromosome 1
58.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr1:134290004-134292547 bp, + strand
From Ensembl annotation of GRCm38

  2544 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1854  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: human myogenin
Gene Tree: Myog

Human
homologs
Human Homolog MYOG, myogenin (myogenic factor 4)
NCBI Gene ID 4656
neXtProt AC  NX_P15173
Human Synonyms  bHLHc3, myf-4, MYF4
Human Chr (Location)  1q31-q41; chr1:203083129-203086038 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations exhibit a severe reduction in muscle mass associated with delayed primary myogenesis and very little secondary myofiber formation, defects of the thoracic skeleton, and perinatal death.
 
Interactions
Myog interacts with 62 markers (Mir7-1, Mir24-1, Mir24-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (61 annotations)
Process cell cycle, cell differentiation, ...
Component nucleus, protein-DNA complex
Function chromatin DNA binding, core promoter binding, ...
External Resources: FuncBase
Expression
Literature Summary: (274 records)
Data Summary: Results (676)    Tissues (284)    Images (225)
Theiler Stages: 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 56
RNA in situ 472
Northern blot 12
Western blot 9
RT-PCR 127
cDNA source data(49)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(107) Genomic(5) cDNA(63) Primer pair(16) Other(23)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000026459 (Evidence)
Entrez Gene17928 (Evidence)
UniGene16528
DFCITC1581588
DoTSDT.534075
NIA Mouse Gene IndexU000825
Consensus CDS ProjectCCDS15306.1
International Mouse Knockout Project StatusMyog
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026459 Ensembl Gene Model | MGI Sequence Detail 2544 C57BL/6J ±  kb
transcript ENSMUST00000027730 Ensembl | MGI Sequence Detail 1479 Not Applicable 
polypeptide ENSMUSP00000027730 Ensembl | MGI Sequence Detail 224 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms All PCR and RFLP(6) : PCR(3) RFLP(3) SNPs within 2kb(45 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
InterPro IPR002546 Myogenic basic muscle-specific protein
Protein Ontology PR:000010877 myogenin
References (Earliest) J:9615 Wright WE, et al., Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD. Cell. 1989 Feb 24;56(4):607-17
(Latest) J:207612 Zhang L, et al., Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development. Dev Biol. 2014 Mar 1;387(1):64-72
All references(365)
Other
accession IDs
MGD-MRK-12775

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory