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Map4 Gene Detail
Summary
  • Symbol
    Map4
  • Name
    microtubule-associated protein 4
  • Synonyms
    MAP 4, Mtap4
  • Feature Type
    protein coding gene
  • IDs
    MGI:97178
    NCBI Gene: 17758
  • Gene Overview
    MyGene.info: MAP4
  • Alliance
  • Transcription Start Sites
    31 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:109931489-110083954 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.83 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    385 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97178
protein coding gene Chr9:109931460-110083955 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035340
protein coding gene Chr9:112041305-112214613 (+)
A/J MGP_AJ_G0035321
protein coding gene Chr9:107982197-108137756 (+)
AKR/J MGP_AKRJ_G0035252
protein coding gene Chr9:110657710-110820216 (+)
BALB/cJ MGP_BALBcJ_G0035316
protein coding gene Chr9:107722917-107880485 (+)
C3H/HeJ MGP_C3HHeJ_G0035024
protein coding gene Chr9:111127216-111308173 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035838
protein coding gene Chr9:115082678-115258050 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032724
protein coding gene Chr9:105211468-105363284 (+)
CAST/EiJ MGP_CASTEiJ_G0034330
protein coding gene Chr9:110943185-111105277 (+)
CBA/J MGP_CBAJ_G0034991
protein coding gene Chr9:119372643-119540561 (+)
DBA/2J MGP_DBA2J_G0035150
protein coding gene Chr9:107442711-107600307 (+)
FVB/NJ MGP_FVBNJ_G0035097
protein coding gene Chr9:106271791-106427448 (+)
LP/J MGP_LPJ_G0035229
protein coding gene Chr9:112347208-112508037 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035137
protein coding gene Chr9:120734009-120909997 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035858
protein coding gene Chr9:110971377-111135690 (+)
PWK/PhJ MGP_PWKPhJ_G0034037
protein coding gene Chr9:107674885-107837247 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033872
protein coding gene Chr9:111055885-111217286 (+)
WSB/EiJ MGP_WSBEiJ_G0034451
protein coding gene Chr9:110853005-111016063 (+)



Homology
more
  • Human Ortholog
    MAP4, microtubule associated protein 4
  • Vertebrate Orthologs
    5
  • Human Ortholog
    MAP4, microtubule associated protein 4
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 4134
    neXtProt AC: NX_P27816
    UniProt: P27816

  • Chr Location
    3p21.31; chr3:47850690-48089279 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Mice homozygous for a gene trapped allele are viable and do not display any overt phenotypic abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 17758 NCBI Gene Model | MGI Sequence Detail 152466 C57BL/6J ±  kb
transcript NM_001205330 RefSeq | MGI Sequence Detail 5776 C57BL/6  
polypeptide P27546 UniProt | EBI | MGI Sequence Detail 1125 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    13 Sequences
  • InterPro Domains
    IPR001084 Microtubule associated protein, tubulin-binding repeat
Molecular
Reagents
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  • All nucleic 36
    cDNA 35
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-12582, MGD-MRK-12588, MGI:2142906
References
more
  • Summaries
    All 47
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:11537 West RR, et al., A model for microtubule-associated protein 4 structure. Domains defined by comparisons of human, mouse, and bovine sequences. J Biol Chem. 1991 Nov 15;266(32):21886-96
  • Latest
    J:228513 Bizet AA, et al., Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nat Commun. 2015;6:8666

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/16/2019
MGI 6.13
The Jackson Laboratory