About   Help   FAQ
Mov10 Gene Detail
Summary
  • Symbol
    Mov10
  • Name
    Moloney leukemia virus 10
  • Synonyms
    Mov-10
  • Feature Type
    protein coding gene
  • IDs
    MGI:97054
    NCBI Gene: 17454
  • Gene Overview
    MyGene.info: MOV10
Location & Maps
more
  • Sequence Map
    Chr3:104794836-104818563 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23728 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 45.87 cM, cytoband F2
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    MOV10, Mov10 RISC complex RNA helicase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MOV10, Mov10 RISC complex RNA helicase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    fSAP113, gb110
  • Links
    NCBI Gene ID: 4343
    neXtProt AC: NX_Q9HCE1

  • Chr Location
    1p13.2; chr1:112674312-112700746 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    72
  • Chemically induced (other)
    1
  • Gene trapped
    69
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Mov10
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022217 VEGA Gene Model | MGI Sequence Detail 23728 C57BL/6J ±  kb
transcript OTTMUST00000052847 VEGA | MGI Sequence Detail 3584 Not Applicable  
polypeptide OTTMUSP00000025110 VEGA | MGI Sequence Detail 1077 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    95 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    9 Sequences
  • EC
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR026122 Putative helicase MOV-10
Molecular
Reagents
less
  • All nucleic 92
    Genomic 4
    cDNA 88

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-12359, MGD-MRK-12377, MGI:2140051
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:6514 Jaenisch R, et al., Chromosomal position and activation of retroviral genomes inserted into the germ line of mice. Cell. 1981 May;24(2):519-29
  • Latest
    J:232981 Kenny PJ, et al., MOV10 and FMRP regulate AGO2 association with microRNA recognition elements. Cell Rep. 2014 Dec 11;9(5):1729-41

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/22/2016
MGI 6.06
The Jackson Laboratory