About   Help   FAQ
Clec10a
Gene Detail
Symbol

Name
ID
Clec10a
C-type lectin domain family 10, member A
MGI:96975
Synonyms
CD301a, Mgl1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
42.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:70156197-70170834 bp, + strand
From VEGA annotation of GRCm38

  14638 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7836  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 western clawed frog; 1 zebrafish

Protein SuperFamily: asialoglycoprotein receptor 1-like protein
Gene Tree: Clec10a

Human
homologs
Human Homolog CLEC10A, C-type lectin domain family 10, member A
NCBI Gene ID 10462
neXtProt AC  NX_Q8IUN9
Human Synonyms  CD301, CLECSF13, CLECSF14, HML, HML2, MGL
Human Chr (Location)  17p13.1; chr17:7074537-7080307 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
 
Homozygotes for a targeted null mutation exhibit elevated red blood cell counts but appear to be otherwise normal.
 
Interactions
Clec10a interacts with 54 markers (Mir16-1, Mir16-2, Mir22, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (48)    Tissues (41)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 26
Western blot 9
RT-PCR 13
cDNA source data(25)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) cDNA(26) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000006033 (Evidence)
Ensembl Gene ModelENSMUSG00000000318 (Evidence)
Entrez Gene17312 (Evidence)
UniGene252405
DFCITC1585536
DoTSDT.101364327, DT.94258450
NIA Mouse Gene IndexU012846
Consensus CDS ProjectCCDS24936.1, CCDS56784.1
International Mouse Knockout Project StatusClec10a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006033 VEGA Gene Model | MGI Sequence Detail 14638 C57BL/6J ±  kb
transcript OTTMUST00000111306 VEGA | MGI Sequence Detail 2332 Not Applicable 
polypeptide OTTMUSP00000062282 VEGA | MGI Sequence Detail 308 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(4) UniProt(15)
Polymorphisms
RFLP(1) : SNPs within 2kb(134 from dbSNP Build 137)    SNPs within 2kb including multiple locations(142)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR018378 C-type lectin, conserved site
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
InterPro IPR005640 Hepatic lectin, N-terminal
Protein Ontology PR:000010910 macrophage asialoglycoprotein-binding protein 1
References
(Earliest) J:5439 Bannerman RM, et al., Hereditary disorders of the red cell in animals. Prog Hematol. 1973;8:131-79
(Latest) J:155676 Westcott DJ, et al., MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity. J Exp Med. 2009 Dec 21;206(13):3143-56
All references(38)
Other
accession IDs
MGD-MRK-12220

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory