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Smcp
Gene Detail
Symbol

Name
ID
Smcp
sperm mitochondria-associated cysteine-rich protein
MGI:96945
Synonyms
Mcsp
Feature Type
protein coding gene
Genetic Map
Chromosome 3
40.14 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr3:92583880-92588997 bp, - strand
From Ensembl annotation of GRCm38

  5118 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
Gene Tree: Smcp
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
On a 129 inbred background, males homozygous for a targeted null mutation produce sperm with reduced motility and capacity to penetrate oocytes resulting in infertility. Noninbred mutant males are normally fertile.
 
Interactions
Smcp interacts with 44 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process binding of sperm to zona pellucida, penetration of zona pellucida, ...
Component cytoplasm, membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 3
cDNA source data(82)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(84) Genomic(1) cDNA(82) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000074435 (Evidence)
Entrez Gene17235 (Evidence)
UniGene331192
DFCITC1579248
DoTSDT.99847155
International Mouse Knockout Project StatusSmcp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074435 Ensembl Gene Model | MGI Sequence Detail 5118 C57BL/6J ±  kb
transcript ENSMUST00000098888 Ensembl | MGI Sequence Detail 848 Not Applicable 
polypeptide ENSMUSP00000096487 Ensembl | MGI Sequence Detail 143 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(11 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000015276 sperm mitochondrial-associated cysteine-rich protein
References
(Earliest) J:3281 Karimpour I, et al., Sequence of the gene encoding the mitochondrial capsule selenoprotein of mouse sperm: identification of three in-phase TGA selenocysteine codons. DNA Cell Biol. 1992 Nov;11(9):693-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)
Other
accession IDs
MGD-MRK-12159

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory